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Key Documents

31388

Sigma-Aldrich

Dextran from Leuconostoc spp.

Mr ~6,000

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About This Item

Linear Formula:
(C6H10O5)n
CAS Number:
9004-54-0
EC Number:
232-677-5
MDL number:
MFCD00130935
UNSPSC Code:
12352201
NACRES:
NA.25
Product 31388 is not currently sold in your country. Contact Technical Service

biological source

(Leuconostoc spp)

Quality Level

200

form

powder

mol wt

Mr ~6,000

color

white

mp

483  °C ((901 °F ))

solubility

water: 1.5 g/10 mL, colorless to faintly yellow

storage temp.

room temp

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

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This Item
313903139231387
葡聚糖 来源于明串珠菌 属 Mr ~6,000

31388

葡聚糖 来源于明串珠菌 属

Sigma-Aldrich

31390

葡聚糖 来源于明串珠菌 属

葡聚糖 来源于明串珠菌 属 Mr 450,000-650,000

31392

葡聚糖 来源于明串珠菌 属

葡聚糖 来源于明串珠菌 属 Mr 15,000-25,000

31387

葡聚糖 来源于明串珠菌 属

biological source

(Leuconostoc spp)

biological source

(Leuconostoc spp)

biological source

(Leuconostoc spp)

biological source

(Leuconostoc spp)

solubility

water: 1.5 g/10 mL, colorless to faintly yellow

solubility

water: 0.75 g/5mL, clear

solubility

water: 1.5 g/10 mL, clear, colorless

solubility

water: 0.5 g/5mL, colorless

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

crystalline, solid

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

color

white

color

white

color

white

color

colorless

General description

Dextran is a branched glucan composed of linear α(1→6) linked glucose units and α (1→3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components. Low molecular weight dextrans are often preferred versus high molecular weight dextrans due to their different viscosities, aggregation and permeation properties.
Dextran is an extracellular bacterial polymer of D-glucopyranose. It mostly comprises α-(1→6) linkage in the main chain and a variable number of α-(1→2), α-(1→3), α-(1→4) branched linkages.

Application

Dextran from Leuconostoc spp. has been used:
  • for the glycation of caseinate to investigate the influence of an increase in carbohydrate chain length compared to glucose
  • for the mass calibration of matrix-assisted laser desorption ionization-time of flight mass spectroscopy (MALDI-TOF) for the characterization of silver nanoparticles (AgNPs)
  • as a non-toxic stabilizer to assess the in vivo administration of tungsten trioxide(WO3) nanoparticles

Biochem/physiol Actions

Dextran is used as a drug, particularly as a blood plasma volume expander. It is also useful as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex is a cross-linked dextran that is commonly used for the separation and purification of protein. In the food industry, dextran is applicable as a thickener for jam and ice cream. It hinders the crystallization of sugar and augments moisture retention. This preserves the flavor and appearance of several food items.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    WXBF5410V
    BCCJ1352
    WXBD6949V
    BCCF2262
    BCCD7246

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    Thomas Rath et al.
    Nephron. Clinical practice, 114(1), c81-c88 (2009-11-06)
    Intravenous iron supplementation is a basic principle in the therapy of haemodialysis (HD) patients with renal anaemia. In the Iron Dextran in Renal Anaemia (IDIRA) study, we analysed the efficacy of a therapy with low-molecular-weight iron dextran (LMW-ID) in stable
    Eugen Sisu et al.
    Rapid communications in mass spectrometry : RCM, 20(2), 209-218 (2005-12-15)
    A combined methodology for obtaining at the preparative scale and characterization by nanoelectrospray ionization (nanoESI) quadrupole time-of-flight (QTOF) mass spectrometry (MS) and tandem MS (MS/MS) of linear polysaccharides modified at the reducing end is presented. Two polydisperse maltodextrins (1000 and
    R J Stenekes et al.
    Biomaterials, 22(13), 1891-1898 (2001-06-09)
    In this paper, a novel method is presented for the preparation of dextran hydrogels and microspheres, based on crystallization. Although dextrans are known to be well soluble in water, precipitation was observed in concentrated aqueous solutions of low molecular weight
    Rohan P Choraghe et al.
    Life (Basel, Switzerland), 11(2) (2021-02-13)
    At host-pathogen contact sites with Candida albicans, Dectin-1 activates pro-inflammatory signaling, while DC-SIGN promotes adhesion to the fungal surface. We observed that Dectin-1 and DC-SIGN collaborate to enhance capture/retention of C. albicans under fluid shear culture conditions. Therefore, we devised
    Yuichi Ozaki et al.
    Circulation journal : official journal of the Japanese Circulation Society, 76(4), 922-927 (2012-02-04)
    Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, the former requires injection of contrast media for image acquisition. The increased total amount of contrast media for FD-OCT image acquisition may
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    Dextran and Polysaccharides Overview

    Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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