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Merck
CN

27673

Collagenase Substrate

BioReagent, ≥95.0% (HPLC), powder, suitable for quantitative collagenase determination

Synonym(s):

Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

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About This Item

Empirical Formula (Hill Notation):
C27H36N6O9
CAS Number:
13075-38-2
Molecular Weight:
588.61
NACRES:
NA.32
PubChem Substance ID:
57648264
UNSPSC Code:
12352204
EC Number:
235-973-2
MDL number:
MFCD00077021
Beilstein/REAXYS Number:
6039452

Key Documents

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Product Name

Collagenase Substrate, BioReagent, For quantitative collagenase determination

InChI key

YMMPZCZOLKBHAP-IHPCNDPISA-N

InChI

1S/C27H36N6O9/c1-17(26(39)40)31-25(38)20-10-6-12-33(20)22(35)14-28-21(34)13-29-24(37)19-9-5-11-32(19)23(36)15-30-27(41)42-16-18-7-3-2-4-8-18/h2-4,7-8,17,19-20H,5-6,9-16H2,1H3,(H,28,34)(H,29,37)(H,30,41)(H,31,38)(H,39,40)/t17-,19-,20-/m0/s1

SMILES string

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@@H]2CCCN2C(=O)CNC(=O)OCc3ccccc3)C(O)=O

product line

BioReagent

assay

≥95.0% (HPLC)

form

powder

shipped in

wet ice

storage temp.

−20°C

Quality Level

200

Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6953
BCCN3255
BCCM2606
BCCH8503
BCCJ7424

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M Fukumoto et al.
Fertility and sterility, 36(6), 746-750 (1981-12-01)
Collagenolytic enzyme activities presumed to play an important role in ovulation were investigated in the human follicular apex, base, and granulosa cell layer throughout the ovarian cycle. Those analyzed were human ovarian collagenase, 2,4-dinitrophenyl-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH peptidase, N-carbobenzoxy-Gly-Pro-Gly-Gly-Pro-Ala peptidase, and alpha-N-benzoyl-DL-arginine beta-naphthylamide
Michael J Boulware et al.
The Journal of physiology, 586(12), 2873-2888 (2008-05-03)
The functionality of the endoplasmic reticulum (ER) as a Ca(2+) storage organelle is supported by families of Ca(2+) pumps, buffers and channels that regulate Ca(2+) fluxes between the ER lumen and cytosol. Although many studies have identified heterogeneities in Ca(2+)
Mihwan Kim et al.
Bioscience, biotechnology, and biochemistry, 68(7), 1533-1540 (2004-07-28)
A Bacillus vietnamensis metalloprotease (BVMP) with high affinity toward collagen was isolated and purified from the culture supernatant of Bacillus vietnamensis 11-4 occurring in Vietnamese fish sauces. The BVMP gene was cloned and its nucleotide and coded amino acid sequences
John R Lukens et al.
PloS one, 4(10), e7619-e7619 (2009-10-31)
The liver possesses distinct tolerogenic properties because of continuous exposure to bacterial constituents and nonpathogenic food antigen. The central immune mediators required for the generation of effective immune responses in the liver environment have not been fully elucidated. In this
Christopher M Schonhoff et al.
Hepatology (Baltimore, Md.), 48(5), 1665-1670 (2008-08-09)
Cyclic adenosine monophosphate (cAMP) stimulates hepatic bile acid uptake by translocating sodium-taurocholate (TC) cotransporting polypeptide (Ntcp) from an endosomal compartment to the plasma membrane. Rab4 is associated with early endosomes and involved in vesicular trafficking. This study was designed to
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