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27667

Sigma-Aldrich

Collagenase Chromophore-Substrate

for use at 320 nm

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Synonym(s):
4-Phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg-OH dihydrate
Empirical Formula (Hill Notation):
C38H52N10O8 · 2H2O
CAS Number:
118081-33-7
Molecular Weight:
812.91
EC Number:
241-086-1
MDL number:
MFCD00151529
UNSPSC Code:
12352204
PubChem Substance ID:
329753009
NACRES:
NA.32

description

for quantitative collagenase determination

Quality Level

100

form

powder or crystals

shipped in

wet ice

storage temp.

−20°C

SMILES string

O.O.CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc2ccc(cc2)\N=N\c3ccccc3)C(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@H](CCCNC(N)=N)C(O)=O

InChI

1S/C38H52N10O8.2H2O/c1-24(2)21-29(33(50)42-22-32(49)47-19-7-12-30(47)34(51)43-28(36(53)54)11-6-18-41-37(39)40)44-35(52)31-13-8-20-48(31)38(55)56-23-25-14-16-27(17-15-25)46-45-26-9-4-3-5-10-26;;/h3-5,9-10,14-17,24,28-31H,6-8,11-13,18-23H2,1-2H3,(H,42,50)(H,43,51)(H,44,52)(H,53,54)(H4,39,40,41);2*1H2/b46-45+;;/t28-,29+,30+,31+;;/m1../s1

InChI key

PZUVBRODNGRBBH-UHGWVMIQSA-N

Related Categories

Biochem/physiol Actions

Collagenase chromophore-substrate is specifically cleaved by collagenase between the leucine and glycine residues. Digestion of the colored hydrophilic substrate leads to the colored fragment PAZ-Pro-Leu-OH (II) and the colorless tripeptide H-GJy-Pro-D-Arg-OH (III).

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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