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Merck
CN

271R-2

Inhibin, alpha (MRQ-63) Rabbit Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-63, monoclonal
Application:
IHC (p)
Citations:
9
Technical Service
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-63, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (271R-24), vial of 0.1 mL concentrate Research Use Only (271R-24-RUO), vial of 0.5 mL concentrate (271R-25), vial of 1.0 mL concentrate (271R-26), vial of 1.0 mL concentrate Research Use Only (271R-26-RUO), vial of 1.0 mL pre-dilute Research Use Only (271R-27-RUO), vial of 1.0 mL pre-dilute ready-to-use (271R-27), vial of 7.0 mL pre-dilute ready-to-use (271R-28), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (271R-28-RUO)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

adrenal cortex

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... INHA(3623)

General description

Inhibin is a peptide hormone that inhibits FSH secretion from the pituitary. Inhibin is a dimer that consists of an alpha and beta subunit. In normal tissue, anti-inhibin alpha labels granulosa cells of the ovary, sertoli and Leydig cells of the testis, and the zona reticularis of the adrenal cortex. Anti-inhibin alpha has demonstrated utility in the identification of sex cord-stromal tumors and adrenal cortical tumors.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Inhibin, alpha Positive Control Slides, Product No. 271S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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W G McCluggage et al.
Journal of clinical pathology, 51(2), 114-116 (1998-05-29)
To investigate the immunohisto-chemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. Also, to determine whether immunostaining with this antibody is useful in differentiating between adrenal cortical neoplasms and other tumours involving the
K A Iczkowski et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(8), 774-779 (1998-08-28)
We compared the expression of inhibin A, chromogranin, synaptophysin, S-100 protein, cytokeratins AE1/AE3, 7, and 20, and estrogen and progesterone receptors in testicular sex cord-stromal tumors: 11 Sertoli cell tumors, 3 Sertoli cell adenomas (nodules), 26 benign Leydig cell tumors
F Kommoss et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(7), 656-664 (1998-08-04)
We investigated 203 ovarian tumors and tumor-like lesions for inhibin expression using a monoclonal anti-inhibin alpha antibody. Inhibin was present in the tumor cells in all 14 primary adult granulosa cell tumors (4 luteinized) plus 3 metastatic, all 10 primary



Global Trade Item Number

SKUGTIN
271R-26-RUO04061837570131