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Safety Information

200R-1

Sigma-Aldrich

Androgen Receptor (SP107) Rabbit Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

¥1,002.92

Please contact Customer Service for Availability
Request a Bulk Order

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP107, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (200R-14)
vial of 0.5 mL concentrate (200R-15)
bottle of 1.0 mL predilute (200R-17)
vial of 1.0 mL concentrate (200R-16)
bottle of 7.0 mL predilute (200R-18)

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This Item
06680071375SAB5500007
Androgen Receptor (SP107) Rabbit Monoclonal Antibody

200R1

Androgen Receptor (SP107) Rabbit Monoclonal Antibody

抗雄激素受体抗体 from rabbit, purified by affinity chromatography

06680

抗雄激素受体抗体

抗磷酸化雄激素受体（Ser81）抗体 Upstate®, from rabbit

071375

抗磷酸化雄激素受体（Ser81）抗体

Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody

SAB5500007

Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal

conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

unconjugated

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

human

species reactivity

rat, human

species reactivity

human

species reactivity

human (tested)

clone

SP107, monoclonal

clone

polyclonal

clone

polyclonal

clone

SP242, monoclonal

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

technique(s)

ChIP: suitable (ChIP-seq), flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

western blot: suitable

technique(s)

immunohistochemistry: 1:100

General description

As a member of the steroid hormone superfamily, androgen receptor functions within distinctintracellular compartments to mediate cellular growth and transcriptional activation ofandrogen-regulated signaling pathways. Androgen receptor expression is broadly distributedacross a variety of normal tissue types. The anti-androgen receptor may be used as an aid toidentify carcinomas of the breast and prostate.

Quality


IVD
IVD
IVD
RUO

Linkage

Androgen Receptor Positive Control Slides, Product No. 200S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000424987
    0000424987
    0000407908
    0000407908
    0000401996

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    Laura C Collins et al.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 924-931 (2011-05-10)
    Previous studies have demonstrated that androgen receptor is expressed in many breast cancers, but its expression in relation to the various breast cancer subtypes as defined by molecular profiling has not been studied in detail. We constructed tissue microarrays from
    A K Roy et al.
    Annals of the New York Academy of Sciences, 949, 44-57 (2002-01-25)
    Androgens are C-19 steroids secreted primarily from the testes and adrenals that play a critical role in reproduction. Reproductive functions of androgens are mediated through coordination of diverse physiological processes ranging from brain functions to specific cell proliferation and apoptosis.
    J M Hakimi et al.
    World journal of urology, 14(5), 329-337 (1996-01-01)
    Androgen-receptor (AR) gene mutations have been found in clinical prostate cancer, both prior to hormonal therapy and in hormone-refractory disease that persists despite androgen-ablative therapy. Thus, mutations that are present in late-stage disease might arise prior to therapy rather than
    Carlos Cordon-Cardo et al.
    The Journal of clinical investigation, 117(7), 1876-1883 (2007-06-09)
    We have developed an integrated, multidisciplinary methodology, termed systems pathology, to generate highly accurate predictive tools for complex diseases, using prostate cancer for the prototype. To predict the recurrence of prostate cancer following radical prostatectomy, defined by rising serum prostate-specific
    R S Carroll et al.
    Journal of neurosurgery, 82(3), 453-460 (1995-03-01)
    The predominance of meningiomas in females, the accelerated growth of these tumors during the luteal phase of the menstrual cycle and during pregnancy, and the association between meningiomas and breast cancer have led to a number of studies examining the
    View All Related Papers

    Articles

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    IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

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