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Merck
CN

195855

Precocene I

99%

Synonym(s):

7-Methoxy-2,2-dimethyl-3-chromene

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About This Item

Empirical Formula (Hill Notation):
C12H14O2
CAS Number:
Molecular Weight:
190.24
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
241-566-0
MDL number:
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InChI key

CPTJXGLQLVPIGP-UHFFFAOYSA-N

InChI

1S/C12H14O2/c1-12(2)7-6-9-4-5-10(13-3)8-11(9)14-12/h4-8H,1-3H3

SMILES string

COc1ccc2C=CC(C)(C)Oc2c1

assay

99%

form

liquid

refractive index

n20/D 1.56 (lit.)

bp

68 °C/0.1 mmHg (lit.)

density

1.052 g/mL at 25 °C (lit.)

application(s)

agriculture
environmental

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup


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M I Baldellou et al.
Revista espanola de fisiologia, 42(3), 315-317 (1986-09-01)
Antigonadotropic activities of Precocene 1 (P1), Precocene 2 (P2) and Ethoxyprecocene 2 (EP2) on the seed bug Oxycarenus lavaterae (F.) (Heteroptera, Lygaeidae), are reported. EP2 proved to be the most active compound followed by P2 and P1, which agrees with
V Ravindranath et al.
Biochemical pharmacology, 36(4), 441-446 (1987-02-15)
The mechanism of the hepatotoxicity of precocene I has been investigated in male, Sprague-Dawley rats. Administration of a single dose of precocene I caused a large depletion of liver glutathione (GSH) levels that was both time and dose dependent. Concomitant
Atsushi Yaguchi et al.
Journal of agricultural and food chemistry, 57(3), 846-851 (2009-02-05)
Inhibitors of deoxynivalenol production by Fusarium graminearum are useful for protecting crops from deoxynivalenol contamination. We isolated precocenes and piperitone from the essential oils of Matricaria recutita and Eucalyptus dives, respectively, as specific inhibitors of the production of 3-acetyldeoxynivalenol, a
A Fodor et al.
General and comparative endocrinology, 74(1), 18-31 (1989-04-01)
Precocenes (PI and PII) and 114 of their analogs (PAs) were synthetized and tested on C. remanei embryos for their precocene-like (P-like) activities resulting in unusual development at sublethal doses. The P-like activity was quantitated by plotting the probit of
Angela M Bernard et al.
Organic letters, 4(15), 2565-2567 (2002-07-19)
[reaction: see text] The thionium ion, generated through a cyclopropylcarbinyl-cyclobutyl ring expansion, is, for the first time, intramolecularly intercepted by activated aromatic rings to generate new versatile 2a-methyl-8b-(phenylsulfanyl-1,2a,3,8b-tetrahydro-2H-cyclobuta[c]chromenes.

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