195855
Precocene I
99%
Synonym(s):
7-Methoxy-2,2-dimethyl-3-chromene
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About This Item
Empirical Formula (Hill Notation):
C12H14O2
CAS Number:
Molecular Weight:
190.24
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.25
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Assay
99%
form
liquid
refractive index
n20/D 1.56 (lit.)
bp
68 °C/0.1 mmHg (lit.)
density
1.052 g/mL at 25 °C (lit.)
application(s)
agriculture
environmental
SMILES string
COc1ccc2C=CC(C)(C)Oc2c1
InChI
1S/C12H14O2/c1-12(2)7-6-9-4-5-10(13-3)8-11(9)14-12/h4-8H,1-3H3
InChI key
CPTJXGLQLVPIGP-UHFFFAOYSA-N
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J Vanden Broeck et al.
European journal of biochemistry, 254(1), 90-95 (1998-07-04)
This study describes the cloning of two cDNAs encoding three serine-protease-inhibiting peptides, SGPI I, II and III, which were recently identified from ovarian extracts of the desert locust, Schistocerca gregaria. The first cDNA codes for the precursor polypeptides of SGPI
D Taylor et al.
Experimental & applied acarology, 14(2), 123-136 (1992-05-01)
Vitellogenin (Vg) concentrations in the hemolymph and ovarian development were studied in Ornithodoros moubata after treatment with precocenes 1 (P1) and 2 (P2). Precocene was dissolved in acetone or DMSO and topically applied to the dorsal surface of ticks: (1)
A H Hammond et al.
Biochemical pharmacology, 44(7), 1461-1464 (1992-10-06)
Cytochrome P450 (P450)-dependent activities in homogenates of rat hepatocytes cultured for 96 hr in serum-free and serum-containing medium were compared. Benzphetamine and erythromycin N-demethylases, 7-methoxy- and propoxy-coumarin O-dealkylases, p-nitrophenol hydroxylase and 7-ethoxy- and pentoxy-resorufin O-dealkylases were all maintained at higher
A F Hamnett et al.
Life sciences, 32(24), 2747-2753 (1983-06-13)
The corpora allata from adult female Locusta migratoria metabolize precocene I (7-methoxy-2,2-dimethyl-2H-benzo [b]pyran to cis- & trans-precocene I dihydrodiols (3,4-dihydro-7-methoxy-2,2-dimethyl-2H-benzo [b]pyran-3,4-diol). Derivatization of the dihydrodiols with (-)menthoxy acetyl chloride allowed complete resolution of all four optical isomers. When [4-3H]-precocene I
V Ravindranath et al.
Biochemical pharmacology, 36(4), 441-446 (1987-02-15)
The mechanism of the hepatotoxicity of precocene I has been investigated in male, Sprague-Dawley rats. Administration of a single dose of precocene I caused a large depletion of liver glutathione (GSH) levels that was both time and dose dependent. Concomitant
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