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Merck
CN

17927

9-Oxo-10(9H)-acridineacetic acid

derivatization grade (HPLC), ≥99.0% (T)

Synonym(s):

(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone

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About This Item

Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
227508
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Product Name

9-Oxo-10(9H)-acridineacetic acid, derivatization grade (HPLC), ≥99.0% (T)

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

SMILES string

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

grade

derivatization grade (HPLC)

assay

≥99.0% (T)

form

solid

mp

~289 °C (dec.)

Quality Level

Application

9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC; Building block in pharmaceutics

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Tolerance or hyperreactivity to interferon induction by sodium salt of 9-oxo-10-acridineacetic acid and analogs in mice and in the mouse macrophage cultures.
Szulc B, Inglot AD, Inglot O.
Arch. Immunol. Ther. Exp., 35, 389-395 (1987)
V M Frolov et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 18-27 (2012-11-20)
The use of reamberin and cycloferon combination for increasing the antibacterial therapy efficacy in patients with chronic sepsis (CS) was studied. It was shown that the combination provided more rapid elimination of the CS exacerbation symptoms, normalization of the hematologic
V M Frolov et al.
Likars'ka sprava, (1-2)(1-2), 102-107 (2012-10-06)
The effect of the immunotropic drug cycloferon and herbal medicine resources on the basis of Cynara scolimus L. on the blood cytokine profile in the patients with chronic viral hepatitis C (CVHC) in medical rehabilitation (MR) period. Established that prior
S.A. Lyakhov et al.
Pharmazie, 49, 367-367 (1994)
Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)

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