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Key Documents

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Safety Information

16005

Sigma-Aldrich

Brij® L23

main component: tricosaethylene glycol dodecyl ether

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

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250 G
CN¥830.50
1 KG
CN¥1,870.18

CN¥830.50

Available to ship onApril 11, 2025Details

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250 G
CN¥830.50
1 KG
CN¥1,870.18

About This Item

CAS Number:
9002-92-0
MDL number:
MFCD00080891
UNSPSC Code:
12161900
PubChem Substance ID:
57647536
NACRES:
NA.21

CN¥830.50

Available to ship onApril 11, 2025Details

Request a Bulk Order

description

non-ionic

form

pellets

CMC

91 μM

mp

39-43 °C

HLB value

16.9

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

functional group

ether
hydroxyl

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

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Show Differences

1 of 4

This Item
P125416001235989
Brij® L23 main component: tricosaethylene glycol dodecyl ether

16005

Brij® L23

Brij® L23 suitable for Stein-Moore chromatography

P1254

Brij® L23

Brij® L4 main component: tetraethylene glycol dodecyl ether

16001

Brij® L4

Brij® L4 average Mn ~362

235989

Brij® L4

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

solubility

-

solubility

-

solubility

-

cation traces

Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤500 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Na: ≤500 mg/kg, Cr: ≤5 mg/kg, Pb: ≤5 mg/kg, Mg: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

mp

39-43 °C

mp

-

mp

-

mp

-

description

non-ionic

description

non-ionic

description

non-ionic

description

non-ionic

CMC

91 μM

CMC

91 μM

CMC

-

CMC

-

Application

Brij® L23 is a detergent used for measuring the concentration of carbon black in lung tissues.[1] It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2] Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.[3]

Biochem/physiol Actions

Brij® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically.[4] This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.[5]

Other Notes

Non-ionic polyoxyethylene ether.[6] Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.[2]

Legal Information

Brij is a registered trademark of Croda International PLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

>300.2 °F - closed cup

Flash Point(C)

> 149 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCN0695
    BCCM7516
    BCCL7276
    BCCL7277
    BCCL9081

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      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

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    3. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    4. What is the Department of Transportation shipping information for this product?

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    B T Dumas et al.
    Clinica chimica acta; international journal of clinical chemistry, 258(1), 21-30 (1997-02-03)
    A rapid and reliable method for measuring serum albumin employing bromcresol green is described. The addition of albumin to a solution of bromcresol green in a 0.075 M succinate buffer pH 4.20 results in an increase in absorbance at 628
    Cheol-Hong Lim et al.
    Environmental health and toxicology, 28, e2013014-e2013014 (2013-12-05)
    This study was conducted to determine whether nano-sized carbon black exposure results in greater damage in high fat diet-induced overweight rats than normal weight ones and to identify the possible causes of any differences. Two groups of Sprague-Dawley rats allocated
    J K Towns et al.
    Analytical chemistry, 63(11), 1126-1132 (1991-06-01)
    Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution
    R Hommel et al.
    Journal of basic microbiology, 30(4), 297-300 (1990-01-01)
    An improved solubilization procedure for the membrane-bound quinoprotein aldehyde dehydrogenase from Acetobacter rancens CCM 1774 was established. After the first solubilization of membrane enzymes by Brij 35 which provided important extraction of membrane proteins other than aldehyde dehydrogenase, the application
    Hitesh S Deshmukh et al.
    American journal of respiratory cell and molecular biology, 38(4), 446-454 (2007-11-17)
    Chronic obstructive pulmonary disease (COPD), a global public health problem, is characterized by progressive difficulty in breathing, with increased mucin production, especially in the small airways. Acrolein, a constituent of cigarette smoke and an endogenous mediator of oxidative stress, increases
    View All Related Papers

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