Quality Level
Assay
≥90% (TLC)
form
powder or crystals
storage temp.
−20°C
SMILES string
OCC([C@@H](O)[C@H](O)COP(O)(O)=O)=O
InChI
1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h4-6,8-9H,1-2H2,(H2,10,11,12)/t4-,5-/m1/s1
InChI key
FNZLKVNUWIIPSJ-RFZPGFLSSA-N
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Biochem/physiol Actions
D-Xylulose 5-phosphate (D-Xu-5-P) is a metabolite of the hexose monophosphate pathway activating protein phosphatase 2A to mediate the acute effects of carbohydrate feeding on the glycolytic pathway, the coordinated control of enzymes required in fatty acid & triglyceride synthesis. D-Xylulose 5-phosphate is the signal for the coordinated control of lipogenesis. The elevation of D-Xylulose 5-phosphate is the coordinating signal that both acutely activates phosphofructokinase in glycolysis and promotes the action of the transcription factor ChREBP to increase transcription of the genes for the enzymes of lipogenesis, the hexose monophosphate shunt, and glycolysis, all of which are required for the de novo synthesis of fat.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
监管及禁止进口产品
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 883-884, 68-75 (2011-11-15)
The analysis of metabolites in human body fluids remains a challenge because of their chemical diversity and dynamic concentration range. Liquid chromatography (LC) in combination with tandem mass spectrometry (MS/MS) offers a robust, reliable, and economical methodology for quantitative single
Alcoholism, clinical and experimental research, 21(4), 576-580 (1997-06-01)
Thiamine deficiency, a frequent complication of alcoholism, contributes significantly to the development of damage in various organ systems, including the brain. The molecular mechanisms that underlie the differential vulnerabilities to thiamine deficiency of tissue and cell types and among individuals
International journal of cancer, 122(11), 2422-2428 (2008-02-28)
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Clinical science (London, England : 1979), 124(11), 675-684 (2013-01-16)
Physiological hyperglycaemia and hyperinsulinaemia are strong modulators of gene expression, which underpins some of their well-known effects on insulin action and energy metabolism. The aim of the present study was to examine whether acute in vivo exposure of healthy humans
British journal of cancer, 94(4), 578-585 (2006-02-09)
Tumours ferment glucose to lactate even in the presence of oxygen (aerobic glycolysis; Warburg effect). The pentose phosphate pathway (PPP) allows glucose conversion to ribose for nucleic acid synthesis and glucose degradation to lactate. The nonoxidative part of the PPP
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