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Sigma-Aldrich

1,4-Bis(acryloyl)piperazine

BioXtra, suitable for electrophoresis, ≥99.0% (TLC)

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Synonym(s):
1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide
Empirical Formula (Hill Notation):
C10H14N2O2
CAS Number:
6342-17-2
Molecular Weight:
194.23
Beilstein:
745431
MDL number:
MFCD00077661
UNSPSC Code:
41105319
PubChem Substance ID:
329750497
NACRES:
NA.26

product line

BioXtra

Quality Level

100

Assay

≥99.0% (TLC)

form

solid

technique(s)

electrophoresis: suitable

impurities

≤0.05% free acrylic acid

mp

91.5-93.5 °C (lit.)

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

suitability

suitable for electrophoresis

storage temp.

2-8°C

SMILES string

C=CC(=O)N1CCN(CC1)C(=O)C=C

InChI

1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2

InChI key

YERHJBPPDGHCRJ-UHFFFAOYSA-N

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Application


  • Fabrication and application of zwitterionic phosphorylcholine functionalized monoliths with different hydrophilic crosslinkers in hydrophilic interaction chromatography: This study demonstrates the effective use of 1,4-Bis(acryloyl)piperazine as a crosslinker in creating zwitterionic monoliths for chromatographic applications, highlighting its utility in enhancing polymer interactions and selectivity in separation processes (Wang et al., 2020).

  • Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles: This application uses a derivative concept where 1,4-Bis(acryloyl)piperazine could theoretically enhance the self-assembly and stability of redox-sensitive polymeric nanoparticles, offering insights into controlled release and targeted drug delivery systems (Ranucci et al., 2008).

Other Notes

Used as a vinylating agent for graft-copolymerization of different enzymes to cellulose, dextran, or starch; New crosslinking agent for polyacrylamide gels with improved protein separation and detection by silver staining; Increased resolution in 2D-protein electrophoresis.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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