Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

143R-1

Sigma-Aldrich

CD43 (SP55) Rabbit Monoclonal Antibody

Sign Into View Organizational & Contract Pricing
All Photos(1)
UNSPSC Code:
12352200
NACRES:
NA.41

biological source

rabbit

Quality Level

500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP55, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (143R-14)
vial of 0.5 mL concentrate (143R-15)
bottle of 1.0 mL predilute (143R-17)
vial of 1.0 mL concentrate (143R-16)
bottle of 7.0 mL predilute (143R-18)

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SPN(6693)

General description

CD43, also called leukosialin, is expressed on the surface of all leukocytes except for some resting B-cells. It appears to function as an anti-adhesion molecule, mediating repulsion amongst leukocytes. CD43 expression in lymphomas is highly correlated with CD5; thus most T-cell malignancies and a group of small lymphocyte B-cell malignancies [CLL/ SLL, mantle cell lymphoma (MCL), prolymphocytic leukemia] are often positive, while follicular lymphoma (FL) is usually negative. Anti-CD43 is less useful as a lineage marker, but is a sensitive indicator of aberrant B-cell populations. From 70 to 90% of T-cell lymphomas are labeled with this antibody. Plasmacytoma/myeloma and mast cell disease are also labeled with this antibody. No reactivity has been observed with reactive B-cells.

Quality


IVD
IVD
IVD
RUO

Linkage

CD43 Positive Control Slides, Product No. 143S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Manual of Diagnostic Antibodies for Immunohistology (2003)
Diagnostic Immunohistochemistry: Theranostic and Genomic Applications (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service