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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Specific activity:
≥30 U/mg
Biological source:
fermentation/recombinant
biological source
fermentation/recombinant
form
lyophilized solid
specific activity
≥30 U/mg
storage temp.
−20°C
Quality Level
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
One unit corresponds to the amount of enzyme which hydrolyzes 1 μmol diisopropyl fluorophosphate per minute at pH 8.1 and 22 °C
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
监管及禁止进口产品
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Marc-Michael Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 713-718 (2009-01-13)
Hydrogen atoms constitute about half of all atoms in proteins and play a critical role in enzyme mechanisms and macromolecular and solvent structure. Hydrogen atom positions can readily be determined by neutron diffraction, and as such, neutron diffraction is an
Jürgen Gäb et al.
Analytical and bioanalytical chemistry, 396(3), 1213-1221 (2009-11-28)
The enzyme diisopropyl fluorophosphatase (DFPase, EC 3.1.8.2) from the squid Loligo vulgaris effectively catalyzes the hydrolysis of diisopropyl fluorophosphate (DFP) and a number of organophosphorus nerve agents, including sarin, soman, cyclosarin, and tabun. Until now, determination of kinetic data has
Debra A Gearhart et al.
Toxicology and applied pharmacology, 218(1), 20-29 (2006-11-25)
Diisopropylfluorophosphate, originally developed as a chemical warfare agent, is structurally similar to nerve agents, and chlorpyrifos has extensive worldwide use as an agricultural pesticide. While inhibition of cholinesterases underlies the acute toxicity of these organophosphates, we previously reported impaired axonal
Marc-Michael Blum et al.
Biochemistry, 47(18), 5216-5224 (2008-04-10)
A wide range of toxic organophosphorus pesticides and nerve agents is effectively hydrolyzed by the structurally related phosphotriesterase enzymes paraoxonase (PON1) from human plasma and diisopropyl fluorophosphatase (DFPase) from the squid Loligo vulgaris. Both enzymes have potential use as medical
Andreas R Günthert et al.
American journal of obstetrics and gynecology, 191(4), 1164-1172 (2004-10-28)
Eighty percent of human ovarian and endometrial cancers express receptors for luteinizing hormone-releasing hormone (LHRH-R). These receptors can be used for targeted chemotherapy with agents such as AN-152, in which doxorubicin is linked to analog [D-Lys(6)]-LHRH. Direct receptor-mediated antiproliferative effects
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