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138M-1

Sigma-Aldrich

CD138/syndecan-1 (B-A38) Mouse Monoclonal Antibody

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UNSPSC Code:
12352200
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

B-A38, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (138M-14)
vial of 0.5 mL concentrate (138M-15)
bottle of 1.0 mL predilute (138M-17)
vial of 1.0 mL concentrate (138M-16)
bottle of 7.0 mL predilute (138M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:200

isotype

IgG1

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SDC1(6382)

Related Categories

General description

CD138, Syndecan 1, is a transmembrane heparan sulfate proteoglycan, present mainly in a variety of epithelial tissues, participating in cell proliferation, cell migration, intercellular communication, and cell-matrix interactions. In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells. Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues CD138 is also expressed in a variety of epithelial cells.

Quality


IVD
IVD
IVD
RUO

Linkage

CD138/syndecan-1 Positive Control Slides, Product No. 138S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Oksanen et al.
Journal of clinical pathology, 58(4), 376-381 (2005-03-26)
Both Helicobacter pylori and gastro-oesophageal reflux disease (GORD) may cause inflammation in cardiac mucosa. Intestinal metaplasia (IM) is found more often in GORD associated inflammation than in inflammation caused by H pylori, especially in young individuals. To examine morphological differences
Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
Said J, et al.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 261-261 null
A Sebestyén et al.
British journal of haematology, 104(2), 412-419 (1999-03-02)
Syndecan-1, an important transmembrane heparan sulphate proteoglycan is expressed in distinct stages of differentiation of normal lymphoid cells: in pre-B cells and Ig-producing plasma cells; however, its normal function, or presence in lymphoid malignancies, is still largely unknown. The expression
Fionnuala P O'Connell et al.
American journal of clinical pathology, 121(2), 254-263 (2004-02-27)
We evaluated the immunohistochemical profile and specificity of CD138 reactivity in 238 specimens from hematopoietic and nonhematopoietic neoplasms. In 91 bone marrow biopsies, CD138 reactivity was observed for nonneoplastic plasma cells, neoplastic plasma cells in multiple myeloma cases (43/43), and
View All Related Papers

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