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137271

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MES hydrate

EMPROVE® EVOLVE

Pharma Manufacturing

Synonym(s):

MES hydrate, 2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4S · xH2O
CAS Number:
1266615-59-1
Molecular Weight:
195.24 (anhydrous basis)
MDL number:
MFCD00149409
UNSPSC Code:
12161700

biological source

synthetic

Quality Level

400

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

pH

5.5-6.7

useful pH range

5.5-6.7

pKa 

6.1
6.1

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

storage temp.

2-30°C

SMILES string

O.OS(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2

InChI key

MIIIXQJBDGSIKL-UHFFFAOYSA-N

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Application

MES is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.

Packaging

100 g in poly bottle
5, 25, 50 kg in poly drum

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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