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Tricine

EMPROVE® EVOLVE

Pharma Manufacturing

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Synonym(s):
Tricine, N-[Tris(hydroxymethyl)methyl]glycine
Linear Formula:
(HOCH2)3CNHCH2CO2H
CAS Number:
5704-04-1
Molecular Weight:
179.17
Beilstein:
1937804
MDL number:
MFCD00004277
UNSPSC Code:
12161700

biological source

synthetic

Quality Level

400

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested (
Endotoxin, microbial, and trace metals; tested)

pH

7.4-8.8

useful pH range

7.4-8.8

pKa (25 °C)

8.1

pKa 

8.1

suitability

suitable for manufacturing use

storage temp.

2-30°C

SMILES string

OCC(CO)(CO)NCC(O)=O

InChI

1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)

InChI key

SEQKRHFRPICQDD-UHFFFAOYSA-N

Related Categories

Application

Buffer component for separation of low molecular weight peptides.
Buffer component for separation of low molecular weight peptides.Tricine is a biological buffer often referred to as a “Good′s” buffer. The pKa of Tricine is 8.1 which makes Tricine is a good candidate for biological applications that require pH control above physiological. Tricine is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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