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134R-1

Sigma-Aldrich

CD34 (EP88) Rabbit Monoclonal Primary Antibody

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UNSPSC Code:
12352203

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP88, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (134R-14)
vial of 0.1 mL concentrate Research Use Only (134R-14-RUO)
vial of 0.5 mL concentrate (134R-15)
vial of 1.0 mL concentrate (134R-16)
vial of 1.0 mL concentrate Research Use Only (134R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (134R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (134R-17)
vial of 7.0 mL pre-dilute ready-to-use (134R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (134R-18-RUO)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

isotype

IgG

control

placenta, tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... CD34(947)

General description

CD34 is a cell surface glycophosphoprotein expressed on human hematopoietic progenitor cells, vascular endothelial cells, and embryonic fibroblasts. The exact function of CD34 has not yet been determined, though studies have found it may enhance proliferation and block differentiation of stem or progenitor cells, and promote lymphocyte adhesion to vascular endothelium in lymphoid tissues. CD34 expression has also been observed in some gastrointestinal stromal tumors (GIST).

Quality


IVD

IVD

IVD

RUO

Linkage

CD34 Positive Control Slides, Product No. 134S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julie S Nielsen et al.
Journal of cell science, 121(Pt 22), 3683-3692 (2008-11-07)
For almost 30 years, the cell-surface protein CD34 has been widely used as a marker to assist in the identification and Summary isolation of hematopoietic stem cells (HSCs) and progenitors in preparation for bone-marrow transplantation. In addition, it has increasingly
Joanna Kiśluk et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(1), 33-39 (2013-03-08)
Gastrointestinal stromal tumors (GISTs) are the most common cancers of mesenchymal origin in the abdomen. An approximately 95% of GISTs show positive expression of the membrane receptor c-kit (CD117 antigen), which currently constitutes the basis for histopathological diagnosis if this
Goran Torlakovic et al.
Archives of pathology & laboratory medicine, 126(7), 823-828 (2002-06-29)
The immunohistochemical detection of CD34 protein using QBEND10 antibody in bone marrow trephine biopsies was shown recently to be a precise method for quantitation of blasts and a possibly useful approach in diagnosis and classification of myelodysplastic syndrome. To evaluate

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