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Sigma-Aldrich

2-Keto-3-deoxy-D-gluconic acid lithium salt

≥95% (TLC)

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Synonym(s):
3-Deoxy-D-erythro-2-hexulosonic acid lithium salt, KDG, Lithium 2-keto-3-deoxy-D-gluconate
Empirical Formula (Hill Notation):
C6H10O6 · xLi+
CAS Number:
Molecular Weight:
178.14 (free acid basis)
UNSPSC Code:
12352204
NACRES:
NA.32

Assay

≥95% (TLC)

form

powder or crystals

storage temp.

−20°C

InChI

1S/C6H10O6/c7-2-5(10)3(8)1-4(9)6(11)12/h3,5,7-8,10H,1-2H2,(H,11,12)/t3-,5+/m0/s1

InChI key

WPAMZTWLKIDIOP-WVZVXSGGSA-N

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Biochem/physiol Actions

Metabolite in the pentose phosphate pathway, which generates NADPH and pentoses; KDG is an intermediate in the metabolism of glucose and gluconic acid in some pseudomonas strains, of uronic acids in E. coli, and also an important metabolite in the degradation of polygalacturonates in Erwinia chrysanthemi.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

Hygroscopic.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid isomerase in Escherichia coli.
G ASHWELL et al.
The Journal of biological chemistry, 235, 1559-1565 (1960-06-01)
A new pathway of uronic acid metabolism.
A ASHWELL et al.
Biochimica et biophysica acta, 30(1), 186-187 (1958-10-01)
Glucose and gluconic acid oxidation of Pseudomonas saccharophila.
N ENTNER et al.
The Journal of biological chemistry, 196(2), 853-862 (1952-05-01)
G Condemine et al.
Journal of bacteriology, 165(3), 937-941 (1986-03-01)
Mutants of Erwinia chrysanthemi impaired in pectin degradation were isolated by chemical and Mu d(Ap lac) insertion mutagenesis. A mutation in the kduD gene coding for 2-keto-3-deoxygluconate oxidoreductase prevented the growth of the bacteria on polygalacturonate as the sole carbon
Carbohydrate metabolism by Pseudomonas fluorescens. III. Purification and properties of a 6-phosphogluconate dehydrase.
R KOVACHEVICH et al.
The Journal of biological chemistry, 213(2), 745-756 (1955-04-01)

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