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Merck
CN

11184

N-Biotinyl-3,6-dioxaoctane-1,8-diamine trifluoroacetate salt solution

≥95% (TLC), 25 mg/mL in DMSO

Synonym(s):

N-{2-[2-(2-Aminoethoxy)ethoxy]ethyl}biotinamide trifluoroacetate salt, Biotin-DADOO

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About This Item

Empirical Formula (Hill Notation):
C16H30N4O4S · C2HF3O2
CAS Number:
194920-57-5
Molecular Weight:
488.52
NACRES:
NA.32
PubChem Substance ID:
329749322
UNSPSC Code:
12352200
MDL number:
MFCD11114063

Key Documents

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InChI key

SJXUUAFYSXSFNA-HZPCBCDKSA-N

SMILES string

OC(=O)C(F)(F)F.NCCOCCOCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12

InChI

1S/C16H30N4O4S.C2HF3O2/c17-5-7-23-9-10-24-8-6-18-14(21)4-2-1-3-13-15-12(11-25-13)19-16(22)20-15;3-2(4,5)1(6)7/h12-13,15H,1-11,17H2,(H,18,21)(H2,19,20,22);(H,6,7)/t12-,13-,15-;/m0./s1

assay

≥95% (TLC)

concentration

25 mg/mL in DMSO

solubility

DMF: soluble

storage temp.

2-8°C

Application

Utilized to biotinylate thiomethyl and thiosulfate derivatives of carboxymethylcellulose through a DCC coupling reaction Labeling targets include glycoproteins, glycopeptides, and any aldehyde- or keto group-containing component (e.g., haptens) Utilized to synthesize a biotin-estradiol conjugate (i.e., biotinoyl-diaminodioxaoctane-estradiol derivative) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.

Packaging

Sold on the basis of grams of solution.
Product 11184-1G contains 1 gram of solution (approximately 910 microliters), at a concentration of 25 mg/mL (~23 mg N-Biotinyl-3,6-dioxaoctane-1,8-diamine trifluoroacetate salt).

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBT5542
1383666V
1383666

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S Miyatake et al.
Molecular and cellular biology, 11(12), 5894-5901 (1991-12-01)
The region extending from -40 to -54 of the 5'-flanking region of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene shows homology to sequences found in the 5'-flanking regions of other cytokine genes, those encoding interleukin-4 (IL-4), IL-5, and granulocyte colony-stimulating

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