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11184

Sigma-Aldrich

N-Biotinyl-3,6-dioxaoctane-1,8-diamine trifluoroacetate salt solution

≥95% (TLC), 25 mg/mL in DMSO

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Synonym(s):
N-{2-[2-(2-Aminoethoxy)ethoxy]ethyl}biotinamide trifluoroacetate salt, Biotin-DADOO
Empirical Formula (Hill Notation):
C16H30N4O4S · C2HF3O2
CAS Number:
194920-57-5
Molecular Weight:
488.52
MDL number:
MFCD11114063
UNSPSC Code:
12352200
PubChem Substance ID:
329749322
NACRES:
NA.32

Assay

≥95% (TLC)

concentration

25 mg/mL in DMSO

solubility

DMF: soluble

storage temp.

2-8°C

SMILES string

OC(=O)C(F)(F)F.NCCOCCOCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC12

InChI

1S/C16H30N4O4S.C2HF3O2/c17-5-7-23-9-10-24-8-6-18-14(21)4-2-1-3-13-15-12(11-25-13)19-16(22)20-15;3-2(4,5)1(6)7/h12-13,15H,1-11,17H2,(H,18,21)(H2,19,20,22);(H,6,7)/t12-,13-,15-;/m0./s1

InChI key

SJXUUAFYSXSFNA-HZPCBCDKSA-N

Application

Utilized to biotinylate thiomethyl and thiosulfate derivatives of carboxymethylcellulose through a DCC coupling reaction Labeling targets include glycoproteins, glycopeptides, and any aldehyde- or keto group-containing component (e.g., haptens) Utilized to synthesize a biotin-estradiol conjugate (i.e., biotinoyl-diaminodioxaoctane-estradiol derivative) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.

Packaging

Sold on the basis of grams of solution.
Product 11184-1G contains 1 gram of solution (approximately 910 microliters), at a concentration of 25 mg/mL (~23 mg N-Biotinyl-3,6-dioxaoctane-1,8-diamine trifluoroacetate salt).

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Miyatake et al.
Molecular and cellular biology, 11(12), 5894-5901 (1991-12-01)
The region extending from -40 to -54 of the 5'-flanking region of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene shows homology to sequences found in the 5'-flanking regions of other cytokine genes, those encoding interleukin-4 (IL-4), IL-5, and granulocyte colony-stimulating

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