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08657

Sigma-Aldrich

7-Amino-1,3-naphthalenedisulfonic acid monopotassium salt monohydrate

BioReagent, suitable for fluorescence, ≥98.0% (T)

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Synonym(s):
2-Naphthylamine-6,8-disulfonic acid monopotassium salt, mono-Potassium 7-amino-1,3-naphthalenedisulfonate monohydrate, AGA
Empirical Formula (Hill Notation):
C10H8KNO6S2 · H2O
CAS Number:
303137-06-6
Molecular Weight:
359.42
Beilstein:
4835047
MDL number:
MFCD00287288
UNSPSC Code:
12352106
PubChem Substance ID:
329748623
NACRES:
NA.32

product line

BioReagent

Quality Level

100

Assay

≥98.0% (T)

solubility

H2O: soluble

fluorescence

λex 310 nm; λem 450 nm in 0.1 M phosphate pH 7.0

suitability

suitable for fluorescence

SMILES string

O.[K+].Nc1ccc2cc(cc(c2c1)S(O)(=O)=O)S([O-])(=O)=O

InChI

1S/C10H9NO6S2.K.H2O/c11-7-2-1-6-3-8(18(12,13)14)5-10(9(6)4-7)19(15,16)17;;/h1-5H,11H2,(H,12,13,14)(H,15,16,17);;1H2/q;+1;/p-1

InChI key

SHURQDDWGCOLFA-UHFFFAOYSA-M

Application

To label carbohydrates, this fluorescent reagent reacts with the reducing termini of oligosaccharids to form a Schiffs base, which can then be stabilized by reducing it with sodium cyanoborohydride.

Other Notes

Fluorescent label for carbohydrates

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Analysis of fluorescently labeled oligosaccharides by capillary electrophoresis and eletrospray ionization mass spectroscopy
Wolff, M. W., et al.
Biotechnol. Tech., 13, 797-797 (1999)
Mingyan Hei et al.
American journal of perinatology, 32(8), 725-732 (2014-12-24)
This study aimed to compare the outcomes for symmetrical (sSGA) versus asymmetrical (aSGA) small for gestational age (SGA) < 32 weeks preterm infants. A total of 12,179 eligible infants admitted to the Canadian tertiary neonatal intensive care units (NICUs) over a 7-year-period
K B Lee et al.
Analytical biochemistry, 205(1), 108-114 (1992-08-15)
Polyacrylamide gel electrophoresis (PAGE) and capillary zone electrophoresis (CZE) were used to measure the activity of glycosyltransferases. Acceptor molecules were prepared by reductive amination of the monopotassium 7-amino-1,3-naphthalenedisulfonic acid (AGA) Schiff base with sugars. The resulting sugar conjugates were purified
Ben J Evans et al.
Cytogenetic and genome research, 145(3-4), 243-252 (2015-06-13)
Genome duplication creates redundancy in proteins and their interaction networks, and subsequent smaller-scale gene duplication can further amplify genetic redundancy. Mutations then lead to the loss, maintenance or functional divergence of duplicated genes. Genome duplication occurred many times in African
Rafael Parra-Medina et al.
PloS one, 10(5), e0124040-e0124040 (2015-05-06)
Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in susceptible individuals, and its prevalence varies depending on the studied population. Given that information on CD in Latin America is scarce, we aimed to investigate the
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