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Merck
CN

07076

Castor Oil, Hydrogenated,Ethoxylated

Synonym(s):

Cremophor® RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil, RH 40

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About This Item

CAS Number:
61788-85-0
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
MFCD01771439

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impurities

≤0.2% sulfated ash (verfied on random samples only), ≤1 ppm ethylene oxide, ≤10 ppm dioxan, ≤10 ppm heavy metals (verfied on random samples only), ≤2 ppm arsenic (verfied on random samples only), ≤2.0% water, ≤5000 ppm acetic acid, ≤620 ppm diethylene glycol, ≤620 ppm ethylene glycol

ign. residue

≤0.25% (verfied onrandom samples only)

acid value

≤0.8 mg KOH/g

hydroxyl value

60‑75 mg KOH/g

iodine value

≤1.0 g I2/100 g

saponification value

50‑60 mg KOH/g

suitability

suitable for acidity or alkalinity

Quality Level

100

Related Categories

Application

Castor Oil, Hydrogenated,Ethoxylated is used to solubilize vitamins, water insoluble active substances and essential oils in water or mixtures of water and alcohol.

Analysis Note

congealing temperature 16-26°C

Other Notes

Castor Oil, Hydrogenated, Ethoxylated is the brand name for a range of non-ionic polyethoxylated detergents. It was developed for use as solubilizers and emulsifiers.

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

467.6 °F

flash_point_c

242 °C

Regulatory Information

植物油/植物胶产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6035
BCCM7386
BCCL5059
BCCL5058
BCCM3260

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Christofori M R R Nastiti et al.
Pharmaceutics, 12(2) (2020-02-06)
Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated to increase the potential of resveratrol as a skin targeting antioxidant. Nanoformulations were prepared using a spontaneous emulsification method, and
Masafumi Uematsu et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 27(5), 437-444 (2011-07-01)
To determine the element that modulates benzalkonium chloride (BAC) toxicity by using a new electrophysiological method to evaluate acute corneal barrier dysfunction induced by travoprost Z with sofZia (Travatan Z(®)), travoprost with 0.015% BAC (Travatan(®)), and its additives. Corneal transepithelial
Shoukath M Ali et al.
International immunopharmacology, 10(3), 325-330 (2009-12-23)
Develop Nanosomal formulation of Tacrolimus to provide safer alternative treatment for organ transplantation patients. Investigate safety, tolerability and pharmacokinetics of Nanosomal Tacrolimus formulation versus marketed Tacrolimus containing polyoxyl 60 hydrogenated castor oil (HCO-60) that causes side effects. Nanosomal Tacrolimus was
Yun-Seok Rhee et al.
Archives of pharmacal research, 30(1), 114-123 (2007-03-03)
The aim of this study was to develop an aqueous parenteral formulation containing itraconazole (ITZ) using an o/w microemulsion system. A mixture of benzyl alcohol and medium chain triglyceride (3/1) was chosen as the oil phase. Pseudoternary phase diagrams of
Shu Yu et al.
Vaccine, 30(36), 5425-5436 (2012-06-20)
Oil-in-water emulsions are potent human adjuvants commonly used in effective pandemic influenza vaccines; however, such emulsions that can induce both Th1-biased systemic immune responses and strong mucosal immune responses via an easy method of administration are lacking. To address this
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