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06116

Sigma-Aldrich

6-(Iodoacetamido)fluorescein

suitable for fluorescence, ≥95% (HPLC)

Synonym(s):

6-IAF, N-(3′,6′-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-6-yl)-2-iodoacetamide

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About This Item

Empirical Formula (Hill Notation):
C22H14INO6
CAS Number:
73264-12-7
Molecular Weight:
515.25
Beilstein:
13738833
MDL number:
MFCD00155654
UNSPSC Code:
12352200
PubChem Substance ID:
329748213
NACRES:
NA.32

Quality Level

100

Assay

≥95% (HPLC)

λmax

~489 nm in DMSO

fluorescence

λex 488 nm; λem 542 nm in DMF

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccc(NC(=O)CI)cc45)c1

InChI

1S/C22H14INO6/c23-10-20(27)24-11-1-4-14-17(7-11)22(30-21(14)28)15-5-2-12(25)8-18(15)29-19-9-13(26)3-6-16(19)22/h1-9,25-26H,10H2,(H,24,27)

InChI key

YRDPEKZBFANDFE-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG7344
BCBV9004
BCBZ9997
BCBS0767V
BCBM9754V

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Consuelo Walss-Bass et al.
The international journal of neuropsychopharmacology, 11(8), 1097-1104 (2008-05-10)
Although atypical antipsychotics are widely known to induce alterations in lipid and glucose metabolism, the mechanisms by which these alterations occur remain unknown. Several recent studies have shown that atypical antipsychotics induce oxidative stress and oxidative cell injury by increasing
Chemical modifications of proteins as an aid to sequence analysis.
Alex F Carne
Methods in molecular biology (Clifton, N.J.), 211, 333-354 (2002-12-20)
Hajo Haase et al.
Analytical biochemistry, 333(1), 19-26 (2004-09-08)
In the cellular environment, the sulfur ligands in zinc/thiolate coordination sites of proteins can be oxidized with concomitant mobilization of zinc. The characterization of such "redox zinc switches" requires the determination of three species, i.e., the zinc-containing complex and the
Muhammad R Baig et al.
Journal of psychiatric practice, 16(5), 325-333 (2010-09-23)
There is increasing concern about the serious metabolic side effects and neurotoxicity caused by atypical (second-generation) antipsychotics. In a previous study by our group (Walss-Bass et al. Int J Neuropsychopharmacol 2008;11:1097-104), using a novel proteomic approach, we showed that clozapine
Identification and localization of the 5-iodoacetamido-fluorescein reporter site on dog kidney Na,K-ATPase.
M Steinberg et al.
Progress in clinical and biological research, 273, 39-44 (1988-01-01)
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