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Merck
CN

05989

Bixin

≥90.0% (HPLC)

Synonym(s):

6-Methyl hydrogen (9Z)-6,6′-diapocarotene-6,6’-dioate, 9-cis-6,6′-Diapo-ψ,ψ-carotenedioic acid 6-methyl ester, Natural orange 4

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About This Item

Empirical Formula (Hill Notation):
C25H30O4
CAS Number:
6983-79-5
Molecular Weight:
394.50
PubChem Substance ID:
329748187
UNSPSC Code:
12352202
NACRES:
NA.32
EC Number:
230-248-7
Colour Index Number:
75120

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InChI

1S/C25H30O4/c1-20(12-8-14-22(3)16-18-24(26)27)10-6-7-11-21(2)13-9-15-23(4)17-19-25(28)29-5/h6-19H,1-5H3,(H,26,27)/b7-6+,12-8+,13-9+,18-16+,19-17+,20-10+,21-11+,22-14+,23-15-

InChI key

RAFGELQLHMBRHD-SLEZCNMESA-N

assay

≥90.0% (HPLC)

form

powder

λ

in chloroform

UV absorption

λ: 465-475 nm Amax

storage temp.

−20°C

Quality Level

100

General description

Bixin is a carotenoid and the principal colouring component of Annatto food colouring (E160b), which has a long history of use in the food industry for the colouring of a wide range of food commodities.
Bixin is a methyl ester of a dibasic fatty acid. On treating with alkali, it is hydrolyzed to form water soluble norbixin. It is obtained in pure form from annatto seeds. Bixin is a carotenoid and estimated as yolk and skin pigmenter.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN3918
BCCK9446
BCCJ6951
BCCH2724
BCCG8507

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Florence Bouvier et al.
Science (New York, N.Y.), 300(5628), 2089-2091 (2003-06-28)
Bixin, also known as annatto, is a seed-specific pigment widely used in foods and cosmetics since pre-Columbian times. We show that three genes from Bixa orellana, native to tropical America, govern bixin biosynthesis. These genes code for lycopene cleavage dioxygenase
Muntha K Reddy et al.
Journal of agricultural and food chemistry, 53(23), 9268-9273 (2005-11-10)
The most abundant water soluble natural food colors are betacyanins and anthocyanins. Similarly, lycopene, bixin, beta-carotene, and chlorophyll are water insoluble colors. Pure betanin, bixin, lycopene, chlorophyll, beta-carotene, and cyanidin-3-O-glucoside were isolated from Beta vulgaris, Bixa orellana,Lycopersicum esculentum, Spinacia oleracea
S Kiokias et al.
European journal of clinical nutrition, 57(9), 1135-1140 (2003-08-30)
To determine whether dietary supplementation with a natural carotenoid mixture counteracts the enhancement of oxidative stress induced by consumption of fish oil. A randomised double-blind crossover dietary intervention. Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University
Carotenoids as Colorants and Vitamin A Precursors: Technological and Nutritional Applications (2012)
Extraction of bixin from annatto seeds using combined technologies
Taham, T., et al.
Journal of Supercritical Fluids, 100, 175-183 (2015)
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