04668
O-Phospho-L-homoserine lithium salt
≥95% (TLC)
Synonym(s):
O-Phosphono-L-homoserine lithium salt, L-2-Amino-4-hydroxybutyric acid 4-phosphate lithium salt, L-Homoserine O-phosphate lithium salt, H-Hse(PO3H2)-OH
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About This Item
Empirical Formula (Hill Notation):
C4H10NO6P · xLi+
CAS Number:
Molecular Weight:
199.10 (free acid basis)
UNSPSC Code:
12352209
NACRES:
NA.26
SMILES string
[P](=O)(OCC[C@H](N)C(=O)O)(O)O
InChI
1S/C4H10NO6P/c5-3(4(6)7)1-2-11-12(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
InChI key
FXDNYOANAXWZHG-VKHMYHEASA-N
assay
≥95% (TLC)
form
powder
optical activity
[α]/D -18.0±2.0°, c = 1 in H2O
color
white to off-white
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
Metabolite in glycine, serine and threonine metabolism. In higher plants, O-phosphohomoserine represents a branch point between the methionine and threonine biosynthetic pathways.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Hongtao Li et al.
Science (New York, N.Y.), 315(5814), 1000-1003 (2007-02-17)
Pathogenic bacteria use the type III secretion system to deliver effector proteins into host cells to modulate the host signaling pathways. In this study, the Shigella type III effector OspF was shown to inactivate mitogen-activated protein kinases (MAPKs) [extracellular signal-regulated
Stereochemistry of the hydrogen removal at position 3 in the enzymic synthesis of L-threonine from O-phospho-L-homoserine.
Fuganti, C.
Journal of the Chemical Society. Chemical Communications, 7, 337-339 (1979)
D Bartlem et al.
Plant physiology, 123(1), 101-110 (2000-05-12)
In higher plants, O-phosphohomoserine (OPH) represents a branch point between the methionine (Met) and threonine (Thr) biosynthetic pathways. It is believed that the enzymes Thr synthase (TS) and cystathionine gamma-synthase (CGS) actively compete for the OPH substrate for Thr and
An ATP-independent phosphotransferase in higher plants. The formation of O-phospho-L-homoserine from O-succinyl-L-homoserine and phosphate.
Haginiwa, J., et al.
Chemical & Pharmaceutical Bulletin, 27, 1710-1713 (1979)
G E Gilbert et al.
Biochemistry, 32(37), 9577-9585 (1993-09-21)
Phosphatidylserine, a negatively charged lipid, is exposed on the platelet membrane following cell stimulation, correlating with the expression of factor VIII receptors. We have explored the importance of the negative electrostatic potential of phosphatidylserine vs chemical moieties of phosphatidylserine for
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