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Safety Information

M46837

Sigma-Aldrich

Methyl formate

reagent grade, 97%

Synonym(s):

Formic acid methyl ester

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About This Item

Linear Formula:
HCO2CH3
CAS Number:
Molecular Weight:
60.05
Beilstein:
1734623
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.21

grade:
reagent grade
bp:
32-34 °C (lit.)
vapor pressure:
32.81 psi ( 55 °C)
9.21 psi ( 20 °C)

grade

reagent grade

Quality Level

vapor density

2.1 (vs air)

vapor pressure

32.81 psi ( 55 °C)
9.21 psi ( 20 °C)

Assay

97%

form

liquid

autoignition temp.

842 °F

expl. lim.

23 %

impurities

≤3% methyl alcohol

refractive index

n20/D 1.343 (lit.)

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Application

Methyl formate may be used to prepare formamides via amine formaylation.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 1 - STOT SE 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

-2.2 °F - closed cup

Flash Point(C)

-19 °C - closed cup

Regulatory Information

危险化学品

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Catalytic reaction of methyl formate with amines to formamides.
Deutsch J, et al.
Tetrahedron, 65(50), 10365-10369 (2009)
Rotational isomerism in methyl formate and methyl acetate; a low-temperature matrix infrared study using thermal molecular beams.
Blom CE and Gunthard HH.
Chemical Physics Letters, 84(2), 267-271 (1981)
Jean-François Bilodeau et al.
Prostaglandins, leukotrienes, and essential fatty acids, 164, 102215-102215 (2020-12-05)
Cancer has been associated with increased oxidative stress and deregulation of bioactive oxylipins derived from long-chain polyunsaturated fatty acids (LC-PUFA) like arachidonic acid (AA). There is a debate whether ω-3 LC-PUFA could promote or prevent prostate tumor growth through immune
Marine S Da Silva et al.
Prostaglandins, leukotrienes, and essential fatty acids, 126, 64-71 (2017-10-17)
This study aimed to determine whether dairy macronutrients alter markers of inflammation and oxidative stress in endothelial cells. Human endothelial cells (HUVEC) were treated with ruminant trans fatty acids (rTFA), either trans-vaccenic acid (tVA) or trans-palmitoleic acid (tPA), whey protein
Methyl formate as a new building block in C1 chemistry.
Lee JS, et al.
Applied Catalysis, 57(1), 1-30 (1990)

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