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Key Documents

Safety Information

695068

Sigma-Aldrich

Hydrofluoric acid

ACS reagent, 48%

Synonym(s):

HF

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50 MG
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50 MG
CN¥1,606.86

About This Item

Empirical Formula (Hill Notation):
HF
CAS Number:
Molecular Weight:
20.01
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.21

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grade

ACS reagent

vapor density

1.27 (vs air)

vapor pressure

25 mmHg ( 20 °C)

Assay

48%

form

liquid

density

1.15 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 ppm
phosphate (PO43-): ≤1 ppm
sulfate, sulfite (as SO42-): ≤5 ppm

cation traces

As: ≤0.05 ppm
Cu: ≤0.1 ppm
Fe: ≤1 ppm
heavy metals (as Pb): ≤0.5 ppm

SMILES string

[H+].[F-]

InChI

1S/FH/h1H

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1 of 4

This Item
SAB2702141HPA001334SAB4501753
biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

-

product line

Prestige Antibodies® Powered by Atlas Antibodies

product line

-

UniProt accession no.

P49916

UniProt accession no.

P49916

UniProt accession no.

P49917

UniProt accession no.

P18858

Gene Information

human ... LIG3(3980)

Gene Information

human ... LIG3(3980)

Gene Information

human ... LIG4(3981)

Gene Information

human ... LIG1(3978)

General description

Hydrofluoric acid is a solution of hydrogen fluoride (HF) in water. It is composed of hydrogen and fluoride. Hydrofluoric acid is a colorless and highly corrosive liquid. It is commonly used in the manufacture of hydrocarbons and polishing and conditioning glass. Additionally, it is used as a catalyst and in the synthesis of fluoride-containing compounds, and semiconductors. [1] [2]

Application

Hydrofluoric acid solution can be used as a reagent to synthesize:
  • Cyanohydrin alkyl ethers via chiral Bronsted acid-mediated hydrocyanation of vinyl ethers with silyl cyanides.
  • N, N-Dimethylaniline hydrochloride salts via Pd-catalyzed Buchwald-Hartwig amination of aryl triflates with dimethylamines.
It can also be used as a catalyst for the amidation of carboxylic acids with amines to synthesize amides.

Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Hydrofluoric acid burns
    M H, et al.
    Burns : Journal of the International Society For Burn Injuries, 30, 156-159 (2004)
    Hydrofluoric acid
    DW Jr S, et al.
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