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494445

Sigma-Aldrich

Acetonitrile

≥99.93%, biotech. grade

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

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About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
741857
EC Number:
MDL number:
UNSPSC Code:
12191502
eCl@ss:
39031501
PubChem Substance ID:
NACRES:
NA.21

product name

Acetonitrile, biotech. grade, ≥99.93%

grade

biotech. grade

Quality Level

100
200

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

Assay

≥99.93%

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

impurities

≤0.5 ppb as quinine (fluorimetric, 254nm)
≤0.6 μeq/g Titr. base
≤8 μeq/g Titr. acid
<0.001% water

evapn. residue

<0.0002%

color

APHA: <10

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

solubility

water: soluble

density

0.786 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 190 nm Amax: 1.0
λ: 210 nm Amax: 0.03
λ: 220 nm Amax: 0.01
λ: 235 nm Amax: 0.005
λ: 254 nm Amax: ≤0.005
λ: 400 nm Amax: 0.005

format

neat

storage temp.

room temp

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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Related Categories

Application


  • Modified QuEChERS method combined with ultra-performance liquid chromatography-tandem mass spectrometry: This research utilizes acetonitrile′s excellent solvent properties for the detection of cyclopiazonic acid in feeds. The method enhances the efficiency and accuracy of chemical analyses in food safety, demonstrating acetonitrile′s pivotal role in ensuring the quality of agricultural products (Peng et al., 2024).

  • Liquid Chromatographic Enantioseparation of Newly Synthesized Fluorinated Tryptophan Analogs: Highlighting its use in pharmaceutical research, acetonitrile is employed in the chromatographic enantioseparation of complex amino acids, essential for drug development and molecular pharmacology studies (Tanács et al., 2024).

  • Synthesis and Application of 1,8-Naphthalimide Derivatives Fluorescent Probe: Acetonitrile′s versatility is showcased in the synthesis of fluorescent probes for environmental monitoring. Its application in detecting and measuring environmental pollutants highlights its significant impact on ecological research and safety (Negi et al., 2024).

Preparation Note

Product filtered through a 0.2 μm filter.

Other Notes

Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and Characterization of Electrochromic Films Based on 2,5-Bis (2-(3,4-ethylenedioxy) thienyl) pyridine.
Triantou D, et al.
International Journal of Electrochemical Science, 10, 1274-1291 (2015)
Eagleson M.
Concise Encyclopedia Chemistry, 56-56 (1994)
Effect of the acceptor moiety on the electrochemical and electrochromic properties of Donor-Acceptor-Donor polymer films.
Triantou D, et al.
International Journal of Electrochemical Science, 10, 3458-3477 (2015)
Palladium-Catalyzed Oxidative Arylalkylation of Activated Alkenes: Dual C-H Bond Cleavage of an Arene and Acetonitrile.
Wu T, et al.
Angewandte Chemie (International Edition in English), 50(52), 12578-12581 (2011)
Hydrogen peroxide oxygenation of alkanes including methane and ethane catalyzed by iron complexes in acetonitrile.
Shul'pin GB, et al.
Advanced Synthesis & Catalysis, 346(2-3), 317-332 (2004)

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