Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

398276

Sigma-Aldrich

Diisopropyl ether

contains either BHT or hydroquinone as stabilizer, ACS reagent, ≥99.0%

Synonym(s):

Isopropyl ether

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)2CHOCH(CH3)2
CAS Number:
108-20-3
Molecular Weight:
102.17
Beilstein:
1731256
EC Number:
203-560-6
MDL number:
MFCD00008880
UNSPSC Code:
12191502
PubChem Substance ID:
329755910
NACRES:
NA.07

grade

ACS reagent

Quality Level

200

vapor density

3.5 (vs air)

vapor pressure

120 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

827 °F

contains

either BHT or hydroquinone as stabilizer

expl. lim.

1-21 %, 100 °F

impurities

≤0.0007 meq/g Titr. acid
≤0.05% Peroxide (as C6H14O2)

evapn. residue

≤0.01%

color

APHA: ≤25

refractive index

n20/D 1.367 (lit.)

bp

68-69 °C (lit.)

mp

−85 °C (lit.)

density

0.725 g/mL at 25 °C (lit.)

SMILES string

CC(C)OC(C)C

InChI

1S/C6H14O/c1-5(2)7-6(3)4/h5-6H,1-4H3

InChI key

ZAFNJMIOTHYJRJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Diisopropyl ether (DIPE) is branched ether. It is a peroxide forming solvent. This process is catalyzed by heat, light and oxygen. For such solvents small amount of stabilizers like BHT (butylated hydroxytoluene) or hydroquinone is added which removes the free radicals that form peroxides. DIPE has been proposed as a potential alternative oxygenated fuel additive. Several methods have been proposed for its synthesis using acetone as starting material. The molecular structure and conformation has been studied using gas-phase electron diffusion. Its potential carcinogenicity has been studied in Sprague-Dawley rats.

Application

Diisopropyl ether may be used as a solvent in the following processes:
  • Resolution of secondary alcohols.
  • Enantioselective acylation of 1-phenethylamine.
  • Synthesis of aliphatic and aromatic cyanohydrins.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H336

Hazard Classifications

Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

EUH019,EUH066

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-20.2 °F - closed cup

Flash Point(C)

-29 °C - closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Diisopropyl ether one-step generation from acetone-rich feedstocks.
Taylor RJ, et al.
Catalysis Letters, 68(1-2), 1-5 (2000)
Diisopropyl ether syntheses from crude acetone.
Knifton JF and D PSE.
Catalysis Letters, 57(4), 193-197 (1999)
Resolution of secondary alcohols using lipase in diisopropyl ether.
Bevinakatti HS, et al.
The Journal of Organic Chemistry, 54(10), 2453-2455 (1989)
The influence of reaction conditions on the photooxidation of diisopropyl ether.
Collins EM, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 176(1), 86-97 (2005)
Cross-linked enzyme aggregates (CLEAs): stable and recyclable biocatalysts.
Sheldon RA.
Biochemical Society Transactions, 35(6) (2007)
View All Related Papers

Protocols

Solvent Systems for Thin-layer Chromatography of Novabiochem Products

A guide to create solvent systems used for the thin-layer chromatography assay of Novabiochem products.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service