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34874

Sigma-Aldrich

1,1,2-Trichloro-1,2,2-trifluoroethane

suitable for HPLC, ≥99.7% (GC)

Synonym(s):

1,1,2-Trichloro-trifluoroethane, Genetron® 113

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About This Item

Linear Formula:
ClCF2CCl2F
CAS Number:
Molecular Weight:
187.38
Beilstein:
1740335
EC Number:
MDL number:
UNSPSC Code:
41116105
PubChem Substance ID:

vapor pressure

5.5 psi ( 20 °C)

Assay

≥99.7% (GC)

autoignition temp.

1256 °F

technique(s)

HPLC: suitable

impurities

≤0.0005% non-volatile matter
≤0.001% free acid (as CH3COOH)
≤0.005% water (Karl Fischer)

transmittance

235 nm, ≥20%
245 nm, ≥80%
260 nm, ≥98%

refractive index

n20/D 1.358 (lit.)

bp

47-48 °C (lit.)

mp

−35 °C (lit.)

density

1.57 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(Cl)C(F)(Cl)Cl

InChI

1S/C2Cl3F3/c3-1(4,6)2(5,7)8

InChI key

AJDIZQLSFPQPEY-UHFFFAOYSA-N

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General description

1,1,2-Trichloro-1,2,2-trifluoroethane is a chlorofluorocarbon solvent. It affords C2H2F2 and CH4, via Pd/TiO2 catalyzed-reaction with hydrogen at 420-820K. Chlorotrifluoroethene is formed as the main reaction product during the electrodechlorination of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC 113) in the presence of palladium (catalyst).

Application

1,1,2-Trichloro-1,2,2-trifluoroethane may be used for purifying the insulin-like growth factor-I (IGF-I) isolated from the serum of wild western gray kangaroos.

Other Notes

Sales restrictions may apply

Legal Information

Genetron is a registered trademark of Honeywell International Inc.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Ozone 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

383.0 °F

Flash Point(C)

195 °C

Regulatory Information

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Palladium-Assisted Electrodehalogenation of 1, 1, 2-Trichloro-1, 2, 2-trifluoroethane on Lead Cathodes Combined with Hydrogen Diffusion Anodes.
Cabot PL, et al.
Journal of the Electrochemical Society, 144(11), 3749-3757 (1997)
C A Yandell et al.
The Journal of endocrinology, 156(1), 195-204 (1998-03-13)
Insulin-like growth factor-I (IGF-I) and IGF-II have been purified to homogeneity from kangaroo (Macropus fuliginosus) serum, thus this represents the first report of the purification, sequencing and characterisation of marsupial IGFs. N-Terminal protein sequencing reveals that there are six amino
Conversion of 1, 1, 2-trichloro-1, 2, 2-trifluoroethane (CFC113) over TiO2-supported metal and metal oxide catalysts.
Takita Y, et al.
Chemistry Letters (Jpn), 5, 715-718 (1990)
Coadsorption of organic compounds and water vapor on BPL activated carbon. 2. 1, 1, 2-Trichloro-1, 2, 2-trifluoroethane and dichloromethane.
Eissmann RN and Le Van MD.
Industrial & Engineering Chemistry Research, 32(11), 2752-2757 (1993)
H K Xiao et al.
American Industrial Hygiene Association journal, 51(7), 402-404 (1990-07-01)
Results obtained using Fourier transform infrared spectrophotometry (FTIR) for the analysis of samples of carbon disulfide (CS2) eluates containing trichloroethylene (TCE) and Freon from charcoal air sampling tubes were evaluated by comparison with results obtained when using gas chromatography (GC).

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