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Sigma-Aldrich

Calcium phosphate

purum p.a., ≥96.0% (calc. as Ca3(PO4)2, KT)

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Synonym(s):
β-Calcium phosphate tribasic, β-Tricalcium phosphate, tert-Calcium phosphate, tri-Calcium (ortho)phosphate
Empirical Formula (Hill Notation):
Ca3O8P2
CAS Number:
7758-87-4
Molecular Weight:
310.18
EC Number:
231-840-8
MDL number:
MFCD00015984
UNSPSC Code:
12352300
PubChem Substance ID:
329752121
NACRES:
NA.21

grade

purum p.a.

Assay

≥96.0% (calc. as Ca3(PO4)2, KT)

form

powder

loss

≤0.1% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤1000 mg/kg

cation traces

Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤200 mg/kg
K: ≤500 mg/kg
Na: ≤1000 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

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General description

Calcium phosphate (tri calcium phosphate) is a colorless amorphous solid. Its pure form can be obtained by melting CaO with phosphorus (V) oxide at 1100°C. It is used as polish in toothpastes and also in making enamels and opaque glasses.
Calcium phosphate occurs naturally as the minerals: oxydapatit, voelicherite and whitlockite. It is mainly used for developing osteoconductive biomaterials for use as bone substitutes.

Application

Composite of calcium phosphate and a bioactive glass may be employed for the manufacture of customized implants, via 3D-printing process. Dense and homogeneous calcium phosphate coatings may be used for coating the metal implants.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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3D printing of bone substitute implants using calcium phosphate and bioactive glasses.
Bergmann C, et al.
J. Eur. Ceram. Soc., 30(12), 2563-2563 (2010)
Calcium phosphate-based osteoinductive materials.
LeGeros RZ.
Chemical Reviews, 108(11), 4742-4753 (2008)
S Leeuwenburgh et al.
Journal of biomedical materials research, 56(2), 208-215 (2001-05-08)
A new biomimetic method for coating metal implants enables the fast formation of dense and homogeneous calcium phosphate coatings. Titanium alloy (Ti6Al4V) disks were coated with a thin, carbonated, amorphous calcium phosphate (ACP) by immersion in a saturated solution of
Calcium phosphates compounds in conjunction with hydrogel as carrier for BMP-2: a study on ectopic bone formation in rats.
Hulsart-Billstrom G, et al.
Acta Biomaterialia, 7(8), 3042-3049 (2011)
Floor C J van de Watering et al.
Journal of controlled release : official journal of the Controlled Release Society, 164(3), 283-290 (2012-07-18)
Clinical application of calcium phosphate cement (CPC; with incorporated polymeric porogens) in an injectable form implicates that loading methods for growth factors are limited. In view of this, the current study evaluated the in vitro and in vivo release kinetics
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