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13418

Sigma-Aldrich

Sodium carbonate

puriss., meets analytical specification of Ph. Eur., BP, NF, FCC, E500, anhydrous, 99.5-100.5% (calc. to the dried substance)

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Synonym(s):
Calcined soda, Carbonic acid disodium salt, Soda ash
Linear Formula:
Na2CO3
CAS Number:
497-19-8
Molecular Weight:
105.99
Beilstein:
4154566
EC Number:
207-838-8
MDL number:
MFCD00003494
UNSPSC Code:
12352300
PubChem Substance ID:
24848136
NACRES:
NA.21

Quality Level

200

grade

puriss.

Assay

99.5-100.5% (calc. to the dried substance)

form

powder or crystals

quality

meets analytical specification of Ph. Eur., BP, NF, FCC, E500

impurities

alkali hydroxides and bicarbonates, complies
 residual solvents
<5 ppm heavy metals (as Pb)

loss

≤0.5% loss on drying, 300 °C
<0.5% loss on drying, 105°C, 4hrs

pH

12 (25 °C, 106 g/L)

mp

851 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

As: ≤2 mg/kg
Cu: ≤20 mg/kg
Fe: ≤10 mg/kg
Hg: ≤1 mg/kg
Pb: ≤4 mg/kg
Pb: >2 ppm
Zn: ≤20 mg/kg

suitability

complies for appearance of solution

storage temp.

15-25°C

SMILES string

O=C(O[Na])O[Na]

InChI

1S/CH2O3.2Na/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

InChI key

CDBYLPFSWZWCQE-UHFFFAOYSA-L

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Application


  • Development of novel portable NIR spectroscopy process analytical technology (PAT) tool for monitoring the transition of ibuprofen to ibuprofen sodium during wet granulation process: This study emphasizes the use of sodium carbonate in enhancing the sensitivity and efficiency of NIR spectroscopy tools in pharmaceutical manufacturing, showcasing its pivotal role in real-time quality control (Atanaskova E, Geskovski N, 2024).

  • Physicochemical and antioxidant properties of pectin fractions extracted from lemon (Citrus Eureka) peels: Demonstrates the application of sodium carbonate in the extraction processes of biologically active compounds from citrus peels, highlighting its importance in the development of natural antioxidants for health-related products (Su Z, Li G, 2024).

  • Bryophyte-Bioinspired Nanoporous AAO/C/MgO Composite for Enhanced CO2 Capture: The Role of MgO: This research incorporates sodium carbonate to facilitate the creation of innovative materials designed for efficient CO2 capture, addressing environmental concerns through advanced material science (Cortés-Valadez PJ, Cigarroa-Mayorga OE, 2024).

Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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