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13204

Sigma-Aldrich

β-tri-Calcium phosphate

puriss. p.a., ≥98% β-phase basis (unsintered powder)

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Synonym(s):
β-TCP, β-Tricalcium phosphate
Empirical Formula (Hill Notation):
Ca3O8P2
CAS Number:
7758-87-4
Molecular Weight:
310.18
EC Number:
231-840-8
MDL number:
MFCD00015984
UNSPSC Code:
12352300
PubChem Substance ID:
329750099
NACRES:
NA.55

grade

puriss. p.a.

Quality Level

200

Assay

≥98% β-phase basis (unsintered powder)

form

powder

impurities

≤250 mg/kg total sulfur (as SO4) (ICP)
≤50 mg/kg total heavy metals (as lead)

anion traces

chloride (Cl-): ≤100 mg/L

cation traces

As: ≤0.5 mg/kg
Ba: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤5 mg/kg
Cu: ≤1 mg/kg
Hg: ≤0.5 mg/kg
Ni: ≤1 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

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General description

β-tri-Calcium phosphate belongs to the category of calcium-phosphate based ceramics, which has been involved in the preparation of a new biosynthetic material possessing morphogenetic activity that is used as a bone implant.

Analysis Note

Phase Composition (by XRD analysis)
Low crystalinity Hydroxylapatite at unsintered condition.
A high crystalinity ß-Tricalcium phosphate after sintering at 1100C.
ß-TCP: >98% (by x-ray diffraction analysis)
other Ca-P phases as Hydroxylapatite, a-TCP and Pyrophosphate <2.0%

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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A new polyphosphate calcium material with morphogenetic activity
Muller.G.EW, et al.
Materials Letters, 148, 163-166 (2015)
Michael D Weiden et al.
PloS one, 9(10), e108476-e108476 (2014-10-02)
While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1
A H Choi et al.
Journal of dental research, 92(10), 853-859 (2013-07-17)
The purpose of coatings on implants is to achieve some or all of the improvements in biocompatibility, bioactivity, and increased protection from the release of harmful or unnecessary metal ions. During the last decade, there has been substantially increased interest
Floor C J van de Watering et al.
Journal of controlled release : official journal of the Controlled Release Society, 164(3), 283-290 (2012-07-18)
Clinical application of calcium phosphate cement (CPC; with incorporated polymeric porogens) in an injectable form implicates that loading methods for growth factors are limited. In view of this, the current study evaluated the in vitro and in vivo release kinetics
Françoise Borcard et al.
Journal of medicinal chemistry, 55(18), 7988-7997 (2012-08-18)
To control the selective adhesion of human endothelial cells and human serum proteins to bioceramics of different compositions, a multifunctional ligand containing a cyclic arginine-glycine-aspartate (RGD) peptide, a tetraethylene glycol spacer, and a gallate moiety was designed, synthesized, and characterized.
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