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12636

Sigma-Aldrich

Potassium chloride

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E508, 99-100.5% (AT), ≤0.0001% Al

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Linear Formula:
KCl
CAS Number:
Molecular Weight:
74.55
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.21

grade

puriss.

Quality Level

Assay

99-100.5% (AT)

form

powder or crystals

quality

meets analytical specification of Ph. Eur., BP, USP, FCC, E508

impurities

acidity or alkalinity, complies
organic volatile impurities, complies (GC)
residual solvents, complies
≤0.0001% Al
≤0.0005% heavy metals (as Pb)
≤0.003% free acid (as HCl)
≤0.005% free alkali (as KOH)
≤0.02% Mg, alkaline earth metals (as Ca)

loss

≤0.5% loss on drying, 105 °C, 3 h

pH

7

mp

770 °C (lit.)

density

1.98 g/mL at 25 °C (lit.)

anion traces

bromide (Br-): ≤1000 mg/kg
iodide (I-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤1 mg/kg
As: ≤0.5 mg/kg
Ba:, in accordance
Ca: ≤50 mg/kg
Cd: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤10 mg/kg
Hg: ≤1 mg/kg
Mg: ≤50 mg/kg
Na: ≤700 mg/kg
Pb: ≤5 mg/kg
Zn: ≤20 mg/kg

suitability

complies for appearance of solution

SMILES string

[Cl-].[K+]

InChI

1S/ClH.K/h1H;/q;+1/p-1

InChI key

WCUXLLCKKVVCTQ-UHFFFAOYSA-M

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General description

Potassium chloride, an alkali metal halide, is a colorless crystalline salt. Its solubility in water is directly proportional to increase in temperature. It can be prepared from potassium hydroxide, via neutralization reaction with HCl. Calorimetric estimation of the enthalpy of solution of potassium chloride in water has been described.

Application

Potassium chloride may be used in the preparation of fertilizer, potassium hydroxide, potassium carbonate and other potassium slats. It may be used in the calorimetric determination of enthalpy and heat capacity values during the deprotonation (loss of proton H+) of buffers. From these values temperature dependence of the pH of these buffers was calculated.
Potassium chloride can be used as a fertilizer and as a regenerant to soften water. It has been used a buffer for the separation of major purine metabolites in the heart, using reverse phase ion pair chromatography(RPIPC).
May be used for the preparation of phosphate buffered saline, and for the extraction and solubilization of proteins.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Determination of sixteen nucleotides, nucleosides and bases using high-performance liquid chromatography and its application to the study of purine metabolism in hearts for transplantation
Smolenski,T.R, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 527, 414-420 (1990)
McEachern R, et al.
Water Softening with Potassium Chloride: Process, Health, and Environmental Benefits (2009)
H Fukada et al.
Proteins, 33(2), 159-166 (1998-10-21)
Enthalpy and heat capacity changes for the deprotonation of 18 buffers were calorimetrically determined in 0.1 M potassium chloride at temperatures ranging from 5 to 45 degrees C. The values of the dissociation constant were also determined by means of
The use of potassium chloride and tris (hydroxymethyl) aminomethane as standard substances for solution calorimetry.
Rychly R and Pekarek V.
The Journal of Chemical Thermodynamics, 9(4), 391-396 (1977)
Masatoshi Takagaki et al.
Experimental neurology, 252, 12-17 (2013-11-20)
Sedatives in the neurointensive care unit can strongly influence patients' risks of developing secondary brain damage. In particular, isoflurane, a volatile anesthetic, has been recently re-introduced to the neurointensive care unit, and first clinical studies suggest beneficial effects due to

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