SMILES string
N(CCOC(=O)C(=C)C)(C)C.O(CCCC)C(=O)C(=C)C.O(C)C(=O)C(=C)C
InChI
1S/C8H15NO2.C8H14O2.C5H8O2/c1-7(2)8(10)11-6-5-9(3)4;1-4-5-6-10-8(9)7(2)3;1-4(2)5(6)7-3/h1,5-6H2,2-4H3;2,4-6H2,1,3H3;1H2,2-3H3
InChI key
NEDGUIRITORSKL-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
copolymers, butylated methacrylate copolymer
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Basic butylated methacrylate copolyme EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Takatsune Yoshida et al.
International journal of pharmaceutics, 428(1-2), 18-24 (2012-03-13)
The aim of this study was to investigate the effect of Eudragit E/HCl (E-SD) on the reprecipitation of a poorly water-soluble drug, tacrolimus. To evaluate the inhibition of reprecipitation of E-SD, reprecipitation studies on tacrolimus were conducted using a dissolution
Tatiane Pereira de Souza et al.
AAPS PharmSciTech, 8(2), Article 34-Article 34 (2007-07-12)
The aim of this study was to investigate the feasibility of using Eudragit E as a granulating agent for a spray-dried extract from Phyllanthus niruri to obtain tablets containing a high dose of this product. The granules were developed by
M-S Kim
Drug research, 63(6), 326-330 (2013-03-26)
The present study sought to evaluate the pharmacokinetics of dutasteride-loaded Eudragit E nanoparticle in rats. In addition, the study investigated the effect of increasing drug load on the in vitro solubility and dissolution behavior of dutasteride together with its in
Takatsune Yoshida et al.
Drug development and industrial pharmacy, 39(11), 1698-1705 (2012-10-16)
This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under neutral pH conditions. E-SD was used alone as a solid
Sheng Qi et al.
International journal of pharmaceutics, 354(1-2), 158-167 (2008-02-05)
Hot-melt extrusion has attracted considerable interest within the pharmaceutical industry. However, there remains some uncertainty as to how to characterise the physical structure of the extruded systems, particularly in terms of identifying the nature of the drug dispersion within the
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