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Merck
CN

Y0001432

Minoxidil for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Minoxidil, 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide, 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide

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About This Item

Empirical Formula (Hill Notation):
C9H15N5O
CAS Number:
38304-91-5
Molecular Weight:
209.25
NACRES:
NA.24
PubChem Substance ID:
329831424
UNSPSC Code:
41116107
MDL number:
MFCD00063409

Key Documents

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Product Name

Minoxidil for system suitability, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

SMILES string

NC1=CC(=NC(=N)N1O)N2CCCCC2

InChI key

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

minoxidil

manufacturer/tradename

EDQM

mp

272-274 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Related Categories

Application

Minoxidil for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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S W Poff et al.
The Journal of emergency medicine, 10(1), 53-57 (1992-01-01)
A 20-year-old female ingested an unknown quantity of minoxidil tablets as a suicide gesture. She presented to the emergency department about 90 minutes later with tachycardia, diffuse T wave inversion, and S-T segment depression on the ECG, labile hypotension, and
Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil.
K D Meisheri et al.
Biochemical pharmacology, 45(2), 271-279 (1993-01-26)
Topical minoxidil does little for baldness.
Drug and therapeutics bulletin, 27(19), 74-76 (1989-09-18)
[The therapy of androgenetic alopecia with minoxidil].
A Bammel et al.
Deutsche medizinische Wochenschrift (1946), 118(21), 787-789 (1993-05-28)
R C Savin et al.
Dermatologic clinics, 11(1), 55-64 (1993-01-01)
The study and common use of minoxidil have legitimized research in common baldness. Prior to this time, with rare exception, the field was dominated by charlatans and "snake oil merchants." Minoxidil has opened the door to scientific inquiry and allowed
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