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Merck
CN

Y0001324

Sucralfate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Sucrose octasulfate–aluminum complex, Sucralfate

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About This Item

CAS Number:
54182-58-0
NACRES:
NA.24
UNSPSC Code:
41116107

Key Documents

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Product Name

Sucralfate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C11H20O35S8.16Al.40H2O/c12-47(13,14)36-1-3-4(41-49(18,19)20)5(42-50(21,22)23)6(43-51(24,25)26)9(38-3)39-11(2-37-48(15,16)17)8(45-53(30,31)32)7(44-52(27,28)29)10(40-11)46-54(33,34)35;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h3-10H,1-2H2,(H,12,13,14)(H,15,16,17)(H,18,19,20)(H,21,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35);;;;;;;;;;;;;;;;;40*1H2/q;16*+3;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-48/t3-,4-,5+,6-,7+,8+,9+,10-,11-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1......................................................../s1

InChI key

JTZPPHUZZDKEOC-RBQAPOGLSA-A

SMILES string

O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.[O-]S(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS([O-])(=O)=O)O[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O

grade

pharmaceutical primary standard

API family

sucralfate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... PGA5(5222)

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Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Application

Sucralfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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C Belka et al.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 173(5), 247-252 (1997-05-01)
Radiotherapy, a cornerstone in the management of head and neck cancer, pelvic cancer, and esophageal cancer is associated with a marked mucosal toxicity. Pain, malnutrition and diarrhea are the most prevalent clinical symptoms of radiation induced mucosal damage. Because there
Combination sucralfate and histamine2-antagonist therapy.
M A Gales et al.
The Annals of pharmacotherapy, 28(5), 597-600 (1994-05-01)
G Campisi et al.
Minerva stomatologica, 46(6), 297-305 (1997-06-01)
We here describe the pharmacological and pharmacodynamic characteristics of the molecule sucralfate, the aluminum subsalt of sucrose-8-sulphate, introduced in Japan in 1968 as a mucoprotector for the treatment of peptic ulcers. For many years, attempts have been made to broaden
M Lazzaroni et al.
Italian journal of gastroenterology and hepatology, 31 Suppl 1, S48-S53 (1999-06-24)
The efficacy of antacids in the short- and long-term treatment of peptic ulcers, has suggested a possible use in the prevention and in the treatment of non-steroidal anti-inflammatory drug related gastroduodenal lesions. In short-term prevention studies, significant protection against ASA-related
[Sucralfate].
Hideyuki Hiraishi et al.
Nihon rinsho. Japanese journal of clinical medicine, 60 Suppl 2, 688-692 (2002-05-01)
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