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Y0001303

Rizatriptan for system suitability

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Rizatriptan benzoate salt, MK-462, N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
Empirical Formula (Hill Notation):
C15H19N5 · C7H6O2
CAS Number:
145202-66-0
Molecular Weight:
391.47
MDL number:
MFCD00866224
UNSPSC Code:
41116107
PubChem Substance ID:
329831353
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

rizatriptan

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)c1ccccc1.CN(C)CCc2c[nH]c3ccc(Cn4cncn4)cc23

InChI

1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

InChI key

JPRXYLQNJJVCMZ-UHFFFAOYSA-N

Gene Information

human ... HTR1B(3351) , HTR1D(3352)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rizatriptan for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Rizatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

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Y0001302

Rizatriptan benzoate, European Pharmacopoeia (EP) Reference Standard

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Rizatriptan benzoate, British Pharmacopoeia (BP) Reference Standard

18927

2-[2-[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-N,N-dimethylethanamine, reference material

PHR9148

2-[5-(1H-1,2,4-Triazol-1-ylmethyl)-1H-indol-3-yl]ethanol, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9151

N,N-Dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine N-oxide, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR9202

N,N-Dimethyl-2-[1-(methylsulfonyl)-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360

Precautionary Statements

P201 - P280 - P308 + P313

Hazard Classifications

Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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