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Y0001136

Lovastatin for peak identification

Name: Lovastatin for peak identification
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Lovastatin, Mevinolin

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₃₆O₅

CAS Number:

75330-75-5

Molecular Weight:

404.54

UNSPSC Code:

41116107

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key

PCZOHLXUXFIOCF-BXMDZJJMSA-N

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Related Categories

Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lovastatin for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

1370600

Lovastatin, United States Pharmacopeia (USP) Reference Standard

1370611

PHR2277

Pictograms

GHS08

Signal Word

Warning

Hazard Statements

H351,H361f

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 2 - Repr. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats.

Chen-Huan Yu et al.

Carbohydrate polymers, 94(1), 56-62 (2013-04-03)

Two major fractions (RLP-1 and RLP-2) were obtained by purifying the crude polysaccharides extracted from a traditional Chinese herb Rosae Laevigatae Fructus. The average molecular weight of RLP-1 and RLP-2 was 21.5 kDa and 16.1 kDa, respectively. Monosaccharide analysis indicated

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.

Kimberly A Hartwell et al.

Nature chemical biology, 9(12), 840-848 (2013-10-29)

Efforts to develop more effective therapies for acute leukemia may benefit from high-throughput screening systems that reflect the complex physiology of the disease, including leukemia stem cells (LSCs) and supportive interactions with the bone marrow microenvironment. The therapeutic targeting of

Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.

D S Alejandro et al.

Journal of the American Society of Nephrology : JASN, 5(2), 153-160 (1994-08-01)

Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other

The liver and lovastatin.

Keith G Tolman

The American journal of cardiology, 89(12), 1374-1380 (2002-06-14)

The cholesterol-lowering agents, known as statins, have been in use for 15 years and are among the most commonly prescribed drugs. Animal studies and premarketing clinical trials have given signals of hepatotoxicity, primarily minor elevations in serum alanine aminotransferase enzyme

Simultaneous determination of lovastatin and citrinin in red yeast rice supplements by micellar electrokinetic capillary chromatography.

Biljana Nigović et al.

Food chemistry, 138(1), 531-538 (2012-12-26)

Lovastatin is a main component of Monascus purpureus fermented red rice contributing to the lipid-lowering effect. Citrinin is a toxic fermentation by-product which can be found as a contaminant. An accurate, simple and rapid micellar electrokinetic capillary chromatographic method was

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