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Y0000530

Sultamicillin

European Pharmacopoeia (EP) Reference Standard

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Empirical Formula (Hill Notation):
C25H30N4O9S2
CAS Number:
76497-13-7
Molecular Weight:
594.66
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sultamicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C25H30N4O9S2/c1-24(2)17(29-20(32)16(21(29)39-24)27-19(31)15(26)12-8-6-5-7-9-12)22(33)37-11-38-23(34)18-25(3,4)40(35,36)14-10-13(30)28(14)18/h5-9,14-18,21H,10-11,26H2,1-4H3,(H,27,31)/t14?,15-,16?,17-,18-,21?/m0/s1

InChI key

OPYGFNJSCUDTBT-CUUJHUNTSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

WGK

WGK 3

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ralf Smeets et al.
The International journal of oral & maxillofacial implants, 32(6), 1338–1345-1338–1345 (2017-10-14)
To test the antimicrobial properties, surface topography, reaction of surrounding tissue (biocompatibility), and osseointegration of ultrathin implant surfaces containing polysiloxane and nanoscaled silver particles. Implants with polysiloxane coating and nanoscaled silver particles (Ag/SiO Roughness parameters did not differ between all
Efficacy and safety of sultamicillin (750 mg bid) compared with amoxycillin/clavulanate (625 mg tid) in patients with umcomplicated urinary tract infections.
Schutz W.
International Journal of Antimicrobial Agents, 6, S55-S59 (1996)
H A Friedel et al.
Drugs, 37(4), 491-522 (1989-04-01)
Sultamicillin is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would
HPLC for in-process control in the production of sultamicillin.
Laviana L, et al.
Journal of Pharmaceutical and Biomedical Analysis, 31(2), 321-328 (2003)
Efficacy and safety of Sultamicillin (Ampicillin/Sulbactan) and Amoxicillin/Clavulanic Acid in the treatment of upper respiratory tract infections in adults: an open-label, multicentric, randomized trial.
Ferreira J B, et al.
Revista Brasileira de Otorrinolaringologia, 72(1), 104-111 (2006)
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