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Merck
CN

Y0000497

Troxerutin

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Trihydroxyethylrutin, 3′,4′,7-Tris[O-(2-hydroxyethyl)]rutin, Troxerutin

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About This Item

Empirical Formula (Hill Notation):
C33H42O19
CAS Number:
7085-55-4
Molecular Weight:
742.68
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329830984
EC Number:
230-389-4
Beilstein/REAXYS Number:
4778232
MDL number:
MFCD00893813

Key Documents

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Product Name

Troxerutin, European Pharmacopoeia (EP) Reference Standard

InChI key

IYVFNTXFRYQLRP-VVSTWUKXSA-N

InChI

1S/C33H42O19/c1-14-23(38)26(41)28(43)32(49-14)48-13-21-24(39)27(42)29(44)33(51-21)52-31-25(40)22-17(37)11-16(45-7-4-34)12-20(22)50-30(31)15-2-3-18(46-8-5-35)19(10-15)47-9-6-36/h2-3,10-12,14,21,23-24,26-29,32-39,41-44H,4-9,13H2,1H3/t14-,21+,23-,24+,26+,27-,28+,29+,32+,33-/m0/s1

SMILES string

C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(Oc4cc(OCCO)cc(O)c4C3=O)c5ccc(OCCO)c(OCCO)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

grade

pharmaceutical primary standard

API family

troxerutin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Related Categories

Application

Troxerutin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Shows widespread protective effects against oxidative DNA damage induced by D-galactose as well as other types of oxidative stress.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Nisha Susan Thomas et al.
Food & function, 9(10), 5336-5349 (2018-09-28)
Hepatocellular carcinoma (HCC) is the leading cause of cancer death worldwide that lacks proper medical prognosis and treatment. In the present study, the anti-tumoral potential of troxerutin (TX), an ethnomedicine, was examined in relation to its effects on the promoter
Sathish Sampath et al.
Molecular and cellular biochemistry, 395(1-2), 11-27 (2014-06-02)
Troxerutin is a trihydroxyethylated derivative of the flavonoid, rutin. It has been reported to possess the hepatoprotective, nephroprotective, antioxidant, anti-inflammatory, and antihyperlipidemic activities. Troxerutin treatment reduced the blood glucose and glycosylated hemoglobin levels in high-cholesterol-induced insulin-resistant mice and in type-2

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