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Merck
CN

Y0000481

Dibrompropamidine for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dibrompropamidine diisetionate

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About This Item

Empirical Formula (Hill Notation):
C21H30Br2N4O10S2
CAS Number:
Molecular Weight:
722.42
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

[S](=O)(=O)(O)CCO.Brc1c(ccc(c1)\C(=N\[H])\N)OCCCOc2c(cc(cc2)\C(=N\[H])\N)Br

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

dibrompropamidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dibrompropamidine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Certificates of Analysis (COA)

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P Wright et al.
The British journal of ophthalmology, 69(10), 778-782 (1985-10-01)
The first medical cure of a corneal infection due to an Acanthamoeba species is reported. The 44-year-old patient developed a suppurative keratitis associated with an epithelial defect, hypopyon, and secondary glaucoma. Acanthamoeba was confirmed as the causative agent four months
Allergic contact dermatitis from dibrompropamidine cream.
C Lützow-Holm
Contact dermatitis, 20(2), 160-160 (1989-02-01)
R M Richards et al.
Journal of pharmaceutical sciences, 80(9), 861-867 (1991-09-01)
Modifications of antibacterial activity have been demonstrated using combinations of two antibacterials from trimethoprim, sulfonamides (sulfadiazine, sulfamerazine, and silver sulfadiazine), silver nitrate, and dibromopropamidine isethionate, either formulated in a cream base or dissolved in peptone water. The creams were evaluated
Cosmetic contact lens-related Acanthamoeba keratitis.
James McKelvie et al.
Clinical & experimental ophthalmology, 37(4), 419-420 (2009-07-15)
Teresa Løvold Berents et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 129(4), 305-307 (2009-02-24)
There is a high incidence of traumatic wounds. Such wounds often become infected which prolongs the wound healing process. Many patients will contact a pharmacy for antiseptic treatment. Various over-the-counter drugs can help as antiseptic treatment; Brulidine is a cream

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