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Y0000463

Vinorelbine tartrate

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Vinorelbine ditartrate salt
Empirical Formula (Hill Notation):
C45H54N4O8 · 2C4H6O6
CAS Number:
125317-39-7
Molecular Weight:
1079.11
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

vinorelbine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−70°C

InChI

1S/C45H54N4O8.2C4H6O6/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t28?,37-,38+,39+,42+,43+,44-,45-;2*1-,2-/m011/s1

InChI key

CILBMBUYJCWATM-NPJYPKOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Vinorelbine tartrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300,H341,H351,H360D,H372

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2 - Muta. 2 - Repr. 1B - STOT RE 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Acute respiratory failure caused by vinorelbine tartrate in a patient with non-small cell lung cancer.
Uoshima N, et al.
Internal medicine (Tokyo, Japan), 40(8), 779-782 (2001)
Development and Validation of New RPHPLC Method for the Estimation of Vinorelbine in Pharmaceutical Dosage Forms.
Gandhi B M, et al.
International Journal of Research in Pharmacy and Chemistry, 201(3), 3-3 (2013)
Characterization of human cytochrome P450 isoenzymes involved in the metabolism of vinorelbine.
Beulz?Riche D, et al.
Fundamental & Clinical Pharmacology, 19(5), 545-553 (2005)

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