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Y0000405

Salicylic acid impurity B

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Hydroxyisophthalic acid, 4-Hydroxy 1,3-benzenedicarboxylic acid

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About This Item

Linear Formula:
HOC6H3-1,3-(CO2H)2
CAS Number:
636-46-4
Molecular Weight:
182.13
MDL number:
MFCD00010391
UNSPSC Code:
41116107
PubChem Substance ID:
329830938
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

salicylic acid

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(C1=CC(C(O)=O)=C(O)C=C1)=O

InChI

1S/C8H6O5/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3,9H,(H,10,11)(H,12,13)

InChI key

BCEQKAQCUWUNML-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Salicylic acid impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Pricing

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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[In vitro study of the effects of various 4-hydroxyisophthalic acid derivatives on human platelet aggregation].
M De Cunto et al.
Bollettino della Societa italiana di biologia sperimentale, 59(3), 302-308 (1983-03-30)
C P Saint et al.
FEMS microbiology letters, 57(3), 323-328 (1990-06-01)
Genes involved in 4-methyl-o-phthalate and 4-hydroxy-iso-phthalate catabolism reside on a 226-232 kbp catabolic plasmid termed MOP. This was confirmed by transformation and conjugation into an isogenic heat-cured (MOP-) derivative of the wild-type isolate, identified and termed Pseudomonas cepacia Pc701. Transformation
[In vitro study of the mechanism of the platelet anti-aggregant action of picotamide (G 137)].
M Berrettini et al.
Bollettino della Societa italiana di biologia sperimentale, 59(3), 309-315 (1983-03-30)
E Piscopo et al.
Bollettino della Societa italiana di biologia sperimentale, 60(12), 2273-2279 (1984-12-30)
A series of 1,3 -bis-anilides of 4-hydroxyisophthalic acid was prepared and tested for antibacterial and antifungal activity. The prepared compounds (I-XVIII), of general structure (A), (Formula: see text) where Xn = H (I); 2-F (II); 3-F (III); 4-F (IV); 2-Cl
E Piscopo et al.
Bollettino della Societa italiana di biologia sperimentale, 60(6), 1169-1175 (1984-06-30)
The following hydrazono derivatives (I-XIX) of type (A) (sequence in text) where Rn = (sequence in text ) (I-XVII); (sequence in text) (XVIII); -CCl3 (XIX); and Xn = H (I); 2-Cl (II); 3-Cl (III); 4-Cl (IV); 2-NO2 (V); 3-NO2 (VI);

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