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Merck
CN

Y0000259

Diclazuril for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2,6-Dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile

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About This Item

Empirical Formula (Hill Notation):
C17H9Cl3N4O2
CAS Number:
Molecular Weight:
407.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI key

ZSZFUDFOPOMEET-UHFFFAOYSA-N

SMILES string

Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O

InChI

1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)

grade

pharmaceutical primary standard

API family

diclazuril

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Diclazuril for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Warning

Hazard Classifications

Repr. 2 - STOT RE 2

target_organs

Lungs,Liver,lymph node

Storage Class

11 - Combustible Solids

wgk

WGK 2


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A Daugschies et al.
Veterinary parasitology, 149(3-4), 199-206 (2007-09-14)
A multicenter field efficacy study was performed in six farms located in Belgium, France and Germany with a history of suspected coccidiosis outbreaks and the proven presence of Eimeria bovis and/or Eimeria zuernii. At each of these trial sites the
A Y I El-Gendi et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(11), 3209-3214 (2010-08-26)
Following IV injection of doxycycline in a dose of 20 mg kg(-1) b.wt., its serum concentration was best fitted in two-compartment open model in chickens fed either on control or on anticoccidials-containing rations. Diclazuril and halofuginone resulted in a significant
M A Taylor et al.
Veterinary parasitology, 178(1-2), 48-57 (2011-01-15)
Twin lambs at pasture with their ewes, were divided into seven groups of 10 lambs. One group of 10 lambs served as a non-infected, untreated control. Five groups of 10 lambs were infected with 10,000 oocysts of Eimeria crandallis and
Bian-hua Zhou et al.
Parasitology research, 112(4), 1771-1780 (2013-02-19)
Screening the anticoccidial drug targets is very important for developing novel drugs and revealing the molecular basis of drug resistance in coccidia. Due to high effectivity and safety, diclazuril was used widely in the poultry industry. To assess the roles
Kyung-Woo Lee et al.
Research in veterinary science, 93(2), 721-728 (2012-02-04)
This study investigated the effects of various coccidiosis control programs in combination with antibiotic growth promoters (AGPs) on growth performance and host immune responses in broiler chickens. The coccidiosis programs that were investigated included in ovo coccidiosis vaccination (CVAC) with

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