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Safety Information

Y0000193

Carteolol for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Carteolol monohydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2O3 · HCl
CAS Number:
51781-21-6
Molecular Weight:
328.83
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

carteolol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Cl-].N1c2c(c(ccc2)OCC(O)CNC(C)(C)C)CCC1=O.[H+]

InChI

1S/C16H24N2O3.ClH/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13;/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20);1H

InChI key

FYBXRCFPOTXTJF-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carteolol for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Regulatory Information

监管及禁止进口产品

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Kwou-Yeung Wu et al.
The Kaohsiung journal of medical sciences, 23(3), 105-111 (2007-03-29)
In this study, the various antiglaucoma drugs including betaxolol, timolol, levobunolol, carteolol, brimonidine, dipivefrin, dorzolamide, brinzolamide, latanoprost, unoprostone, and pilocarpine were used to investigate the effects of cellular cytotoxicity in cultured bovine corneal endothelial cells. After exposure to the drugs
L Malvitte et al.
The British journal of ophthalmology, 91(1), 29-32 (2006-09-01)
To investigate the ocular surface inflammatory response to chronic topical treatments in patients with glaucoma by measuring the cytokine level in tears using multiplex bead analysis. Tear samples were collected from 21 patients with glaucoma and 12 healthy volunteers. Tears
Li Zhang et al.
Talanta, 82(3), 984-992 (2010-08-04)
A novel method was developed for the analysis of four beta-blockers, namely sotalol, carteolol, bisoprolol, and propranolol, in human urine by coupling carrier-mediated liquid phase microextraction (CM-LPME) to high performance liquid chromatography (HPLC). By adding an appropriate carrier in organic
V Machů
Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 66(1), 39-42 (2010-06-05)
The author follows the influence of combined treatment to the changes in visual field in glaucoma patients. The combined treatment is understood as simultaneous application of eye drops with carteolol as active substance together with systemically applied pentoxyphylin. The paper
Maura Floreani et al.
European journal of pharmacology, 590(1-3), 269-275 (2008-06-24)
This in vitro study was designed to investigate whether carteolol, a non-conventional partial agonists of beta(1)-adrenoceptors, relaxes phenylephrine-constricted rat aorta through activation of the low-affinity state of beta(1)-adrenoceptors or antagonist effect at alpha(1)-adrenoceptors. Carteolol-induced complete concentration-dependent relaxation of phenylephrine-contracted aorta
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