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Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride
Linear Formula:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
CAS Number:
Molecular Weight:
181.70
Beilstein:
3673011
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

heptaminol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CC(N)CCCC(C)(C)O

InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

InChI key

JZNBMCOSOXIZJB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mabrouk Bahloul et al.
American journal of therapeutics, 19(1), e8-17 (2010-08-20)
We analyze in the current study the impact of heptaminol hydrochloride (Heptamyl) administration in patients with septic shock requiring adrenergic support on the duration of vasopressor infusion and on catecholamine delay weaning. In this prospective study were included 49 nonconsecutive
B Pourrias
Annales pharmaceutiques francaises, 49(3), 127-138 (1991-01-01)
Heptaminol hydrochloride is widely used for the treatment for orthostatic hypotension. It continues to elicit controversy as to its mode of action since Loubatières (1951) described its powerful inotropic action on an ischaemic preparation. Twenty five years later it has
K Ueno et al.
Japanese journal of pharmacology, 52(3), 483-488 (1990-03-01)
Heptaminol AMP amidate (HAA), a nucleotide derivative, was found to elevate the intracellular cyclic AMP (cAMP) level of cultured mice spleen cells in a time- and dose-dependent manner. Theophylline and imidazole, when added to the spleen cell culture simultaneously with
P D Drumheller et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(5), 1258-1265 (1991-09-01)
An endothelial cell monolayer with a single mechanically lysed cell was used as a model to examine the extent, kinetics, and nature of local calcium mobilization in the neighborhood of a wound. Individual endothelial cells from confluent monolayers were mechanically
D Milon et al.
Fundamental & clinical pharmacology, 4(6), 695-705 (1990-01-01)
Heptaminol is a molecule with experimental cardiovascular analeptic properties. In this double-blind vs placebo trial, the potency, so far unproven, of the injectable form of a 626 mg dose of heptaminol chlorhydrate on spontaneous or induced orthostatic hypotension (OH), was

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