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Merck
CN

Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride

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About This Item

Linear Formula:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
CAS Number:
Molecular Weight:
181.70
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3673011
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InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

SMILES string

Cl.CC(N)CCCC(C)(C)O

InChI key

JZNBMCOSOXIZJB-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

heptaminol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Emmanouil Lyris et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 827(2), 199-204 (2005-10-26)
A study of the metabolism of isometheptene, an antispasmodic drug, in man and comparison with heptaminol metabolism, is presented in this paper. Isometheptene and two metabolites were detected in human urine after oral administration of a tablet containing isometheptene mucate.
B Fontas et al.
Canadian journal of physiology and pharmacology, 68(7), 791-799 (1990-07-01)
Electrophysiological and transport effects induced by heptaminol hydrochloride were studied in frog epithelium. This tissue, which can easily be maintained in vitro, is a valuable model for studying sodium active transport with hormone-dependent characteristics that reproduce mammalian nephron behavior (notably
Leila Gharibi et al.
Dermatology online journal, 15(4), 16-16 (2009-05-20)
Hair lightening occurred in a patient treated with heptaminol (heptamyl). This patient had chronic renal failure and had been undergoing hemodialysis since 2003. The hair hypopigmentation reversed after stopping the drug. The mechanism of the hair color modification is not
G Thibaut et al.
Angiology, 43(7), 567-571 (1992-07-01)
The purpose of this study was to measure the variations of lymphatic flow. A noninvasive isotopic method was used to achieve a functional exploration of lymphatic circulation. Fifteen subjects were used in the study: 10 healthy subjects and 5 patients
Atul Pathak et al.
European journal of clinical pharmacology, 61(5-6), 471-474 (2005-07-02)
The aim of the present study was to investigate and characterise adverse drug reactions (ADRs) to drugs used in France for orthostatic hypotension (OH). In this prospective and systematic study, 121 consecutive out-patients suffering from primary (Parkinson's disease, pure autonomic

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