Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

Y0000046

Estradiol valerate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

β-Estradiol 17-valerate, 1,3,5(10)-Estratriene-3,17β-diol 17-pentanote

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C23H32O3
CAS Number:
979-32-8
Molecular Weight:
356.50
Beilstein:
2480357
MDL number:
MFCD00056541
UNSPSC Code:
41116107
PubChem Substance ID:
329830826
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

estradiol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

InChI

1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3

InChI key

RSEPBGGWRJCQGY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Estradiol valerate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

1250008

Estradiol, United States Pharmacopeia (USP) Reference Standard

Y0000314

Estradiol for peak identification, European Pharmacopoeia (EP) Reference Standard

E1620000

Estradiol hemihydrate, European Pharmacopoeia (EP) Reference Standard

E1600000

Estradiol benzoate, European Pharmacopoeia (EP) Reference Standard

PHR1353

Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material

Y0000852

Estradiol benzoate for system suitability, European Pharmacopoeia (EP) Reference Standard

1252003

Estradiol cypionate, United States Pharmacopeia (USP) Reference Standard

1251000

Estradiol benzoate, United States Pharmacopeia (USP) Reference Standard

BP729

Estradiol hemihydrate, British Pharmacopoeia (BP) Assay Standard

1254009

Estradiol valerate, United States Pharmacopeia (USP) Reference Standard

1250041

Estradiol Related Compound C, United States Pharmacopeia (USP) Reference Standard

1250020

Estradiol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1252193

Estradiol cypionate System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

Y0001823

Estradiol valerate for system suitability, European Pharmacopoeia (EP) Reference Standard

BP396

Estradiol benzoate, British Pharmacopoeia (BP) Reference Standard

1254031

Estradiol Valerate Identification Mixture, United States Pharmacopeia (USP) Reference Standard

PHR2228

Estradiol 3-Methyl Ether, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2227

Estradiol Impurity L, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2839

Estradiol Cypionate, certified reference material, pharmaceutical secondary standard

PHR2858

Estradiol Benzoate, certified reference material, pharmaceutical secondary standard

PHR2859

Estradiol Related Compound C, pharmaceutical secondary standard, certified reference material

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H351,H361fd,H362,H410

Hazard Classifications

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2

WGK

WGK 3

Regulatory Information

监管及禁止进口产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Sheridan M Hoy et al.
Drugs, 69(12), 1635-1646 (2009-08-15)
Estradiol valerate/dienogest is an oral contraceptive for women that combines the natural estrogen estradiol with the 19-nortestosterone derivative dienogest in a four-phasic formulation. Estradiol valerate/dienogest demonstrated contraceptive efficacy in a large (n = 1377), noncomparative, multicentre study in women aged
B von Schoultz
Climacteric : the journal of the International Menopause Society, 6 Suppl 2, 24-32 (2003-12-13)
A combination of 2 mg estradiol valerate with 2 mg dienogest (E2V/DNG) (Climodien, Schering AG, Berlin, Gemany) is the first continuous combined postmenopausal hormone replacement therapy (HRT) preparation to contain a progestogen with substantial antiandrogenic activity. A study of its
R M Machado-de-Sena et al.
Photodiagnosis and photodynamic therapy, 11(3), 275-282 (2014-05-06)
Vaginal candidiasis (VC) is a disease that affects thousands of women of childbearing age, mainly caused by Candida albicans fungus. Photodynamic therapy (PDT) uses photosensitizing substances that are nontoxic in the dark, but able to produce reactive oxygen species when
Franca Fruzzetti et al.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 28(5), 400-408 (2012-04-04)
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). E(2)-containing combined oral contraceptives (COCs) have demonstrated sufficient ovulation inhibition and acceptable contraceptive efficacy. However, earlier formulations were generally associated with unacceptable
C Egarter et al.
Acta obstetricia et gynecologica Scandinavica, 75(4), 386-393 (1996-04-01)
Two sequential hormone replacement regimens, containing either estradiol valerate plus medroxyprogesterone acetate (E2V/MPA) or conjugated estrogens plus medrogestone (CE/MED), were compared with respect to effects on climacteric symptoms, lipid metabolism, and hemostasis. In an open, multicenter study, 51 perimenopausal women
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service