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X0080000

Xylitol

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
Xylite
Linear Formula:
HOCH2[CH(OH)]3CH2OH
CAS Number:
87-99-0
Molecular Weight:
152.15
Beilstein:
1720523
MDL number:
MFCD00064292
UNSPSC Code:
41116107
PubChem Substance ID:
329830766
NACRES:
NA.24

grade

pharmaceutical primary standard

Agency

EP Reference Standard

API family

xylitol

manufacturer/tradename

EDQM

mp

94-97 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+

InChI key

HEBKCHPVOIAQTA-SCDXWVJYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Xylitol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andréa Gonçalves Antonio et al.
Journal of public health dentistry, 71(2), 117-124 (2011-07-21)
A systematic review of published data was conducted with the aim of assessing the caries preventive effect of consuming xylitol-based candies and lozenges. Electronic and hand searches were performed to find clinical trials concerning the consumption of products containing xylitol
Amir Azarpazhooh et al.
The Cochrane database of systematic reviews, (11)(11), CD007095-CD007095 (2011-11-11)
Acute otitis media (AOM) is the most common bacterial infection among young children in the United States with limitations and concerns over its treatment with antibiotics and surgery. Therefore, effective preventative measures are attractive. A potential preventative measure is xylitol
Tom Birger Granström et al.
Applied microbiology and biotechnology, 74(2), 273-276 (2007-01-12)
Xylitol is the first rare sugar that has global markets. It has beneficial health properties and represents an alternative to current conventional sweeteners. Industrially, xylitol is produced by chemical hydrogenation of D-xylose into xylitol. The biotechnological method of producing xylitol
Jeffrey L Danhauer et al.
International journal of audiology, 49(10), 754-761 (2010-09-30)
A systematic review was conducted to evaluate evidence regarding xylitol, a sugar alcohol, as a prophylaxis for acute otitis media (AOM) in children. The authors searched PubMed and other databases to identify evidence. Criteria for included studies were: appear in
Xi Chen et al.
International journal of biological sciences, 6(7), 834-844 (2010-12-24)
D-Xylitol is found in low content as a natural constituent of many fruits and vegetables. It is a five-carbon sugar polyol and has been used as a food additive and sweetening agent to replace sucrose, especially for non-insulin dependent diabetics.
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