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V0500

Sigma-Aldrich

L-Valine

≥98% (HPLC), suitable for thin layer chromatography (TLC)

Synonym(s):

(S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid

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1 G
CN¥270.75
25 G
CN¥533.88
100 G
CN¥1,368.72
500 G
CN¥4,732.73
1 KG
CN¥8,216.03

CN¥270.75

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1 G
CN¥270.75
25 G
CN¥533.88
100 G
CN¥1,368.72
500 G
CN¥4,732.73
1 KG
CN¥8,216.03

About This Item

Linear Formula:
(CH3)2CHCH(NH2)CO2H
CAS Number:
72-18-4
Molecular Weight:
117.15
Beilstein:
1721136
EC Number:
200-773-6
MDL number:
MFCD00064220
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900695
NACRES:
NA.26

CN¥270.75

Please contact Customer Service for Availability
Request a Bulk Order

Product Name

L-Valine, reagent grade, ≥98% (HPLC)

grade

reagent grade

Quality Level

200

Assay

≥98% (HPLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white

mp

295-300 °C (subl.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

CC(C)[C@H](N)C(O)=O

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1 of 4

This Item
5084894619PHR1172
L-Valine reagent grade, ≥98% (HPLC)

V0500

L-Valine

L-Valine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

50848

L-Valine

L-Valine BioUltra, ≥99.5% (NT)

94619

L-Valine

L-Valine Pharmaceutical Secondary Standard; Certified Reference Material

PHR1172

L-Valine

grade

reagent grade

grade

certified reference material, TraceCERT®

grade

-

grade

certified reference material, pharmaceutical secondary standard

assay

≥98% (HPLC)

assay

-

assay

≥99.5% (NT)

assay

-

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: 50 mg/mL, clear, colorless

solubility

-

solubility

1 M HCl: 0.5 M at 20 °C, clear, colorless

solubility

-

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

mp

295-300 °C (subl.) (lit.)

Application

  • L-Valine has been used as a standard in thin layer chromatography.[1]
  • It has been used as a supplement in Grace′s antheraea medium for the culture of cells and tissue from invertebrates.[2]
  • It has been used in the preparation of starvation media to study the role of relA gene in antibiotic resistance in E. coli.[3]

Biochem/physiol Actions

Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA) maintains a balance among the BCAAs.[4] L-Valine serves as an energy fuel. Long term deficiency of L-Valine leads to growth failure, organ damage and loss of muscle mass.[1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SLCN0175
    SLCN0175
    0000418593
    0000418593
    0000421510

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    Find documentation for the products that you have recently purchased in the Document Library.

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    On the limited role of relA in kanamycin and amino acid starvation induced stringency and subsequent antibiotic cross-protection in Escherichia coli
    Chiang
    Journal of Experimental Microbiology and Immunology, 15, 59-63 (2011)
    Preparation of several media for the culture of tissues and cells from invertebrates.
    Vaughn
    TCA Manual, 527-537 (1977)
    Martin Kohlmeier
    Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
    Zhesi Zhu et al.
    Nucleic acids research, 49(1), 177-189 (2020-12-15)
    Short-chain acylations of lysine residues in eukaryotic proteins are recognized as essential posttranslational chemical modifications (PTMs) that regulate cellular processes from transcription, cell cycle, metabolism, to signal transduction. Lysine butyrylation was initially discovered as a normal straight chain butyrylation (Knbu).
    Zhe Yang et al.
    Cell research, 28(10), 1013-1025 (2018-09-14)
    Adequate protein intake is crucial for the survival and well-being of animals. How animals assess prospective protein sources and ensure dietary amino acid intake plays a critical role in protein homeostasis. By using a quantitative feeding assay, we show that
    View All Related Papers

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