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Safety Information

T9159

Sigma-Aldrich

Trichloroacetic acid

BioXtra, ≥99.0%

Synonym(s):

TCA

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25 ML
¥1,733.89

About This Item

Linear Formula:
Cl3CCOOH
CAS Number:
76-03-9
Molecular Weight:
163.39
Beilstein:
970119
EC Number:
200-927-2
MDL number:
MFCD00004177
UNSPSC Code:
12352106
PubChem Substance ID:
24900586
NACRES:
NB.22

¥1,733.89

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Request a Bulk Order

grade

BioPerformance Certified

Quality Level

200

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

product line

BioXtra

Assay

≥99.0%

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.03%

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

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Show Differences

1 of 4

This Item
91228522082303905
三氯乙酸 BioXtra, &#8805;99.0%

T9159

三氯乙酸

三氯乙酸 BioUltra, &#8805;99.5% (T)

91228

三氯乙酸

三氯乙酸 biotech. grade, redistilled, &#8805;99%

522082

三氯乙酸

三氯乙酸 &#8805;99.5%

303905

三氯乙酸

assay

≥99.0%

assay

≥99.5% (T)

assay

≥99%

assay

≥99.5%

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

H2O: 0.5 M at 20 °C, clear, colorless

solubility

H2O: 0.5 M at 20 °C, clear, colorless

solubility

-

solubility

-

anion traces

sulfate (SO42-): ≤0.05%

anion traces

chloride (Cl-): ≤30 mg/kg, nitrate (NO3-): ≤20 mg/kg, phosphate (PO43-): ≤10 mg/kg, sulfate (SO42-): ≤100 mg/kg

anion traces

-

anion traces

-

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

General description

Trichloroacetic acid (TCA) is an important metabolic product of trichloroethylene (TCE) metabolism.

Application

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.
Trichloroacetic acid has been used:
  • for protein precipitation[1]
  • as a component in the extract solution used for the measurement of malondialdehyde and glutathione[2]
  • to precipitate the transfected and treated cells in [3H]-thymidine incorporation assay[3]

Biochem/physiol Actions

TCA might act as a carcinogen, targeting liver.[4] It might be used as an acid decalcifying agent. TCA helps in nuclear staining.[5]

Pictograms

CorrosionEnvironment
GHS05,GHS09

Signal Word

Danger

Hazard Statements

H314,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

>235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCM8885
    BCCL2519
    BCCM0748
    BCCK4685
    BCCG8679

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    Li J, et al.
    The American Journal of Pathology, 184(2), 556-571 (2014)
    Rapid analysis of total plasma homocysteine by tandem mass spectrometry
    Tuschl K, et al.
    Clinica Chimica Acta; International Journal of Clinical Chemistry, 351(1-2), 139-141 (2005)
    Analysis of malondialdehyde, chlorophyll proline, soluble sugar, and glutathione content in Arabidopsis seedling
    Zhang Z and Huang R
    Bio-protocol, 3, e817-e817 (2013)
    Histophatologic Techniques (2006)
    Bo Chen et al.
    Translational stroke research, 10(1), 91-103 (2018-03-24)
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