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Safety Information

T5411

Supelco

Testosterone solution

1.0 mg/mL in 1,2-dimethoxyethane, drug standard

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CAS Number:
58-22-0
Beilstein:
1915399
MDL number:
MFCD00003654
UNSPSC Code:
41116107
PubChem Substance ID:
329826822
NACRES:
NA.24

grade

drug standard

Quality Level

200

drug control

Home Office Schedule 4.2

concentration

1.0 mg/mL in 1,2-dimethoxyethane

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H]

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI key

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

Gene Information

human ... AR(367) , EBP(10682) , ESR1(2099) , PGR(5241) , SERPINA6(866) , SHBG(6462)
mouse ... Esr1(13982)
rat ... Ar(24208) , Esr1(24890) , Nr3c1(24413) , Nr3c2(25672) , Pgr(25154)

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

H225,H315,H332,H360FD

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

Supplementary Hazards

EUH019

WGK

WGK 1

Flash Point(F)

41.0 °F

Flash Point(C)

5 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Julia K Slezak et al.
Scientific reports, 7(1), 17636-17636 (2017-12-17)
The concentrations of testosterone deposited in hair during hair growth may provide a retrospective reflection of the concentrations of bioactive testosterone in plasma. The objective of this study was to develop a radioimmunoassay with a sufficiently low limit of detection
Line Cantin et al.
The Journal of biological chemistry, 282(42), 30910-30919 (2007-08-23)
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak affinity for the human AR (hAR), thus indicating the need to develop new high-affinity steroidal antiandrogens. Our compounds are specially designed to impede repositioning
Annu A Söderholm et al.
Journal of medicinal chemistry, 48(4), 917-925 (2005-02-18)
We studied the three-dimensional quantitative structure-activity relationships (3D QSAR) of 70 structurally and functionally diverse androgen receptor (AR) binding compounds using the comparative molecular similarity indices analysis (CoMSIA) method. The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and
Arjan van Oeveren et al.
Journal of medicinal chemistry, 49(21), 6143-6146 (2006-10-13)
The androgen receptor is a member of the extended family of nuclear receptors and is widely distributed throughout the body. Androgen therapy is used to compensate for low levels of the natural hormones testosterone (T) and dihydrotestosterone and consists of
Peng Cui et al.
Bioorganic & medicinal chemistry letters, 16(13), 3401-3405 (2006-05-03)
Lisofylline (LSF, 1-(5-R-hydroxyhexyl)-3,7-dimethylxanthine) is an anti-inflammatory agent that protects beta-cells from Th1 cytokine-induced dysfunction and reduces the onset of Type 1 diabetes in non-obese diabetic (NOD) mice. Due to its low potency, poor oral bioavailability, and short half-life, the widespread
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